Results 61 to 70 of about 8,388,586 (287)
Advanced Science, EarlyView.This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen +7 more
wiley +1 more source
Auto‐Downregulation of the Florigen FT Production Prevents Precocious Flowering in Plants
Advanced Science, EarlyView.This study shows that the leaf vein‐expressed FD complexes with the florigen FT to bind DNA motifs in FT promoter, which antagonizes CONSTANS‐mediated FT activation to feedback down‐regulate FT expression. This prevents an excessive induction of FT expression by inductive photoperiods, thereby precluding precocious transition to flowering in ...
Shu Tian, Xiao Luo, Bowen Cui, Yuehui He
wiley +1 more source
An Investigation into the Influence of the Contact Pressure Distribution at the Friction Pair Interface on Disc Brake Squeal [PDF]
The main purpose of this thesis is to investigate the dynamic centre of pressure during a noisy brake application. A novel technique is employed to measure the centre of pressure and contact pressure distribution between the disc/pad interfaces during ...
Ashraf, Naveed
core +3 more sources
Tram Whole-Train Braking Force Management Strategy Based on TCMS
Chengshi guidao jiaotong yanjiu[Objective] Trams require high braking performance and reliability, but they cannot achieve unified distribution and management of the whole train′s braking force.
XU Jie, YANG Chuan, MA Xuan
doaj +1 more source
Research on the automotive braking performance
Highlights in Science, Engineering and Technology, 2023 Due to the rise in vehicle usage, the number of car accidents and the population of injured users have been increasing by years. In order to reduce these problems, this paper has deeply investigated the current development of the optimization of vehicle braking performance.
openaire +1 more source
TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes
Advanced Science, EarlyView.In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang +11 more
wiley +1 more source
Advanced Science, EarlyView.In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.
Haiping Lin +8 more
wiley +1 more source
The Impact of Physical Motion Cues on Driver Braking Performance: A Clinical Study Using Driving Simulator and Eye Tracker. [PDF]
Sensors (Basel), 2022 El Hamdani S +3 more
europepmc +1 more source
Automotive brake pipes characteristics and their effects on brake performance
Ain Shams Engineering Journal, 2012 AbstractDuring the operation of the brakes the behavior of the brake fluid in the brake piping is one element that has a large effect on feel and on transient pressure characteristics. This paper investigates the effect of fitting a brake pipe with different inner diameters to each wheel at the rear axle on the brake performance.Theoretical analysis ...
openaire +1 more source
Advanced Science, EarlyView.The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt +16 more
wiley +1 more source