Results 71 to 80 of about 82,803 (297)

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

open access: yesAdvanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang   +10 more
wiley   +1 more source

A Pressure-Coordinated Control for Vehicle Electro-Hydraulic Braking Systems

open access: yesEnergies, 2018
The characteristics of electro-hydraulic braking systems have a direct influence on the fuel consumption, emissions, brake safety, and ride comfort of hybrid electric vehicles. In order to realize efficient energy recovery for ensuring braking safety and
Yang Yang, Guangzheng Li, Quanrang Zhang
doaj   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

open access: yesAdvanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li   +5 more
wiley   +1 more source

Tram Whole-Train Braking Force Management Strategy Based on TCMS

open access: yesChengshi guidao jiaotong yanjiu
[Objective] Trams require high braking performance and reliability, but they cannot achieve unified distribution and management of the whole train′s braking force.
XU Jie, YANG Chuan, MA Xuan
doaj   +1 more source

Assessment and preliminary design of an energy buffer for regenerative braking in electric vehicles [PDF]

open access: yes
Energy buffer systems, capable of storing the vehicle energy during braking and reusing this stored energy during acceleration, were examined. Some of these buffer systems when incorporated in an electric vehicle would result in an improvement in the ...
Buchholz, R., Mathur, A. K.
core   +1 more source

Analysis of Disengagements in Semi-Autonomous Vehicles: Drivers’ Takeover Performance and Operational Implications [PDF]

open access: yes, 2019
This report analyzes the reactions of human drivers placed in simulated Autonomous Technology disengagement scenarios. The study was executed in a human-in-the-loop setting, within a high-fidelity integrated car simulator capable of handling both manual ...
Agarwal, Shivangi   +5 more
core   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

open access: yesAdvanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo   +8 more
wiley   +1 more source

Baseline tests of the C. H. Waterman Renault 5 electric passenger vehicle [PDF]

open access: yes
The Waterman vehicle, a four passenger Renault 5 GTL, performance test results are presented and characterized the state-of-the-art of electric vehicles. It was powered by sixteen 6-volt traction batteries through a two-step contactor controller actuated
Mcbrien, E. F.   +2 more
core   +1 more source

Hierarchical Artificial Muscle with Nonlinear Elasticity for Antagonistic and Cyclic Robotics

open access: yesAdvanced Science, EarlyView.
We construct hierarchical muscles by plying nylon fibers around a heating wire. The hierarchical muscle shows a J‐shaped passive curve, which shows benefit in antagonistic muscle pair and work accumulation mechanism. We also develop a computational, first‐principle model to understand the physics of both active actuation stroke and passive J‐curve ...
Samuel Tsai   +15 more
wiley   +1 more source

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