Results 51 to 60 of about 56,974 (249)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Generic Branch-Cut-and-Price

, 2010
In this thesis, we present the theoretical background, implementational details and computational results concerning the generic branch-cut-and-price solver ...
Gamrath, Gerald
core   +1 more source

Assessing the economic burden and health-related quality of life in chinese patients with fibrodysplasia ossificans progressiva: a questionnaire survey analysis

Orphanet Journal of Rare Diseases
Background Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare, disabling genetic disorder condition that lacks real-world evidence on disease burden.
Xiaoyang Xu, Xiaoning He, Wei Wu, Yuhang Xin, Qingnan Li, Lei Song, Kexin Li, Jing Wu   +7 more
doaj   +1 more source

ANALISIS PENGARUH BAURAN PEMASARAN TERHADAP PENGAMBILAN KEPUTUSAN MENABUNG BRITAMA PADA PT BANK RAKYAT INDONESIA (PERSERO), Tbk CABANG PEMBANTU PURI ANJASMORO SEMARANG

Keunis, 2019
This study aims to determine the significance of marketing mix variables consisting of product, price, promotion, place, people, processe, and physical evidence of BritAma saving decision making at PT Bank Rakyat Indonesia (Persero), Branch of Puri ...
Kinanda Nor Cahya Ningtias, Embun Duriany Soemarso   +1 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Quantum Subroutines in Branch-Price-and-Cut for Vehicle Routing

IEEE Transactions on Quantum Engineering
Motivated by recent progress in quantum hardware and algorithms, researchers have developed quantum heuristics for optimization problems, aiming for advantages over classical methods.
Friedrich Wagner, Frauke Liers
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

BaPCod - a generic branch-and-price code [PDF]

, 2021
This document presents a user guide for BaPCod version 0.63, a C++ library implementing a generic branch-cut-and-price solver. We give guidelines for installing BaPCod, using its modelling language, BaPCod parameterization, retrieving BaPCod statistics ...
Sadykov, Ruslan, Vanderbeck, François
core   +2 more sources

FI-CAECNet: A Frequency-Aware IMF-Wise Closed-Loop Adaptive Error Correction Network for Stock Price Forecasting

IEEE Access
Stock price forecasting remains challenging because financial time series usually exhibit nonstationarity, strong noise, nonlinear dynamics, multi-scale fluctuations, and abrupt short-term shocks.
Gaofeng Liu
doaj   +1 more source

Otimização no serviço de saúde no estado do Paraná: fluxo de pacientes e novas configurações hierárquicas Optimization of public health services in the state of Paraná: flow of patients and new hierarchical configurations

Gestão & Produção, 2008
This paper presents a proposal for optimizing the public health service in the state of Parana in terms of the flow of patients within the state's boundaries and the regionalization (division) of the state into new hierarchical configurations for this ...
Cassius Tadeu Scarpin, Maria Teresinha Arns Steiner, Gláucio José Cardozo Dias, Pedro José Steiner Neto   +3 more
doaj   +1 more source