Systematically Engineering for Efficient Production of 3‐Methyl‐1‐Butanol in Escherichia coli
An integrated metabolic engineering strategy was established for high‐level 3‐methyl‐1‐butanol biosynthesis in Escherichia coli. Molecular dynamics‐guided semi‐rational engineering of dihydroxyacid dehydratase uncovered and relieved key catalytic bottlenecks, while adaptive laboratory evolution enhanced strain robustness.
Nanfei Geng +6 more
wiley +1 more source
Branched-Chain Amino Acids and Di-Alanine Supplementation Attenuates Muscle Atrophy in a Murine Model of Cancer Cachexia. [PDF]
Colardo M +7 more
europepmc +1 more source
Clickable Microgel Inks Enable Spatioselective, Multi‐Stimuli Programmable Assembly of Materials
Clickable microgel inks enable direct ink writing of hydrogel architectures with intrinsic spatioselective and programmable multi‐responsiveness. By combining pH‐responsive and temperature‐responsive microgel building blocks through Diels‐Alder interparticle crosslinking, the assemblies exhibit controllable swelling and shape changes.
Junho Moon +3 more
wiley +1 more source
Circulating Levels of Branched-Chain Amino Acids Are Associated with Diet: A Cross-Sectional Analysis. [PDF]
Liu K +4 more
europepmc +1 more source
This work successfully fabricated ion‐conductive hydrogels with low hysteresis and high conductivity using 3D printing technology. By adjusting the component ratios, the properties of the hydrogels can be tuned to meet diverse sensing requirements. Finally, a multimodal sensing sign language recognition system was constructed based on this hydrogel ...
Quan Hu +9 more
wiley +1 more source
Deciphering a missing piece of the branched-chain amino acids uptake puzzle: YhjE is an L-isoleucine and L-valine transporter in <i>Escherichia coli</i> K-12. [PDF]
Molev SV +10 more
europepmc +1 more source
Emerging Device Applications From Strong Light–Matter Interactions in 2D Materials
Two‐dimensional semiconductors enable extremely compact optoelectronic devices such as solar cells, sensors, LEDs, and lasers. Their strong light–matter interactions allow efficient light emission, detection, and energy conversion. This review article discusses the recent progress in integrating these materials with optical cavities and nanostructures ...
Janani Archana K +7 more
wiley +1 more source
Plasma branched-chain amino acids and risk of radiation-induced acute skin toxicity in women with breast cancer: results from the ATHENA project. [PDF]
Sharma S +18 more
europepmc +1 more source
Branched chain amino acid perfusion
openaire +1 more source
Catechol Derivative‐Based Bioadhesives: Molecular Design for Precision Medical Adhesion
This study utilizes tree‐inspired side‐chain engineering to graft five catechol derivatives onto PVA, systematically revealing how side‐chain length and substituents regulate adhesion and cohesion properties. Among them, the PVA‐CA patch demonstrates superior tissue adhesion, biocompatibility, and promotes regeneration, establishing a programmable ...
Xueyu Wang +8 more
wiley +1 more source

