Results 81 to 90 of about 148,302 (300)

Detection of a branched alkyl molecule in the interstellar medium: iso-propyl cyanide

, 2014
The largest non-cyclic molecules detected in the interstellar medium (ISM) are organic with a straight-chain carbon backbone. We report an interstellar detection of a branched alkyl molecule, iso-propyl cyanide (i-C3H7CN), with an abundance 0.4 times ...
Belloche, Arnaud, Garrod, Robin T., Menten, Karl M., Müller, Holger S. P.   +3 more
core   +1 more source

SI‐bioATRP in Mesoporous Silica for Size‐Exclusion Driven Local Polymer Placement

Advanced Functional Materials, EarlyView.
An enzyme‐catalyzed surface‐initiated atom transfer radical polymerization (SI‐bioATRP) of an anionic monomer within mesoporous silica particles, using hemoglobin as a catalyst, allows for controlling the location of the formed polymer via size‐exclusion effects between the nanopores and the biomacromolecules, thereby opening routes to functional ...
Oleksandr Wondra, Eleonora Ornati, Robert Lehn, Joanna J. Mikolei, Hergen Breitzke, Raheleh Pardehkhorram, Gerd Buntkowsky, Nico Bruns, Annette Andrieu‐Brunsen   +8 more
wiley   +1 more source

Exploring molecular complexity in the Galactic Center with ALMA

, 2017
The search for complex organic molecules (COMs) in the ISM has revealed chemical species of ever greater complexity. This search relies heavily on the progress made in the laboratory to characterize the rotational spectra of these molecules ...
Belloche, Arnaud
core   +1 more source

Metabolic Modulation Predicts Heart Failure Tests Performance [PDF]

, 2019
The metabolic changes that accompany changes in Cardiopulmonary testing (CPET) and heart failure biomarkers (HFbio) are not well known. We undertook metabolomic and lipidomic phenotyping of a cohort of heart failure (HF) patients and utilized Multiple ...
Abbate, Antonio, Buckley, Leo F., Canada, Justin M., Carbone, Salvatore, Contaifer, Daniel, Jr., Kumar, Naren G., Morriss, Joshua M., Ranasinghe, Asanga D., Trankle, Cory, Van Tassell, Benjamin W., Wijesinghe, Dayanjan S., Wohlford, George   +11 more
core   +3 more sources

Bio‐Inspired Molecular Events in Poly(Ionic Liquids)

Advanced Functional Materials, EarlyView.
Originating from dipolar and polar inter‐ and intra‐chain interactions of the building blocks, the topologies and morphologies of poly(ionic liquids) (PIL) govern their nano‐ and micro‐processibility. Modulating the interactions of cation‐anion pairs with aliphatic dipolar components enables the tunability of properties, facilitated by “bottom‐up ...
Jiahui Liu, Marek W. Urban
wiley   +1 more source

Two highly divergent alcohol dehydrogenases of melon exhibit fruit ripening-specific expression and distinct biochemical characteristics [PDF]

, 2006
Alcohol dehydrogenases (ADH) participate in the biosynthetic pathway of aroma volatiles in fruit by interconverting aldehydes to alcohols and providing substrates for the formation of esters.
A-RS Chen, Alain Latché, B Klein, B Persson, C Aubert, C Tesnière, C Tesnière, C Verriès, D Straeten Van der, Daniel Manríquez, DP Matton, E Moyano, F Fan, F Flores, F Yahyaoui, Farid Regad, Fikri El-Yahyaoui, Francisco B. Flores, G Echeverria, GL Bruxelles De, H Eklund, H Jörnvall, H-P Peng, I El-Sharkawy, I Molina, Islam El-Sharkawy, J Speirs, J Speirs, JC Ingersoll, JD Thompson, Jean-Claude Pech, JJ Salas, JS Peters, K Nakajima, M Guis, MM Bradford, Mondher Bouzayen, N Saitou, P Sarni-Manchado, PK Boss, R Ayub, S Fonseca, S Morrell, S Picton, S Yokoyama, SF Altschul, T Chase Jr, T Longhurst   +47 more
core   +2 more sources

From Clinic to Computation: Multiscale Bioengineering Strategies for Durable Biological Aortic Valve Replacements

Advanced Functional Materials, EarlyView.
Bioprosthetic aortic valves have revolutionized the treatment of aortic stenosis, but their durability is limited by structural valve deterioration (SVD). This review focuses on the pericardial tissue at the heart of these valves, examining how its mechanical properties and calcification drive fatigue and failure.
Gabriele Greco, Pierfrancesco Gaziano, Serena Anglese, Simone Morganti, Carlo de Vincentiis, Ferdinando Auricchio, Michele Marino, Michele Conti   +7 more
wiley   +1 more source

Multi-tissue computational modeling analyzes pathophysiology of type 2 diabetes in MKR mice.

PLoS ONE, 2014
Computational models using metabolic reconstructions for in silico simulation of metabolic disorders such as type 2 diabetes mellitus (T2DM) can provide a better understanding of disease pathophysiology and avoid high experimentation costs.
Amit Kumar, Thomas Harrelson, Nathan E Lewis, Emily J Gallagher, Derek LeRoith, Joseph Shiloach, Michael J Betenbaugh   +6 more
doaj   +1 more source

The refolding of recombinant human liver methylmalonyl-CoA mutase from inclusion bodies produced in Escherichia coli : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]

, 1998
Human methylmalonyl-CoA mutase (hMCM) is an adenosylcobalamin-dependent enzyme that catalyses the structural rearrangement of (R)-methylmalonyl-CoA to succinyl-CoA as pan of the catabolism of the branched chain amino acids valine, leucine and isoleucine,
Hayes, Michelle Marie
core  

Immunometabolism is a key factor for the persistent spontaneous elite control of HIV-1 infection [PDF]

, 2019
Approximately 25% of elite controllers (ECs) lose their virological control by mechanisms that are only partially known. Recently, immunovirological and proteomic factors have been associated to the loss of spontaneous control. Our aim was to perform a
Alba, Verónica, ECRIS integrated in the Spanish AIDS Research Network, Herrero, Pol, Jimenez-Leon, María Reyes, Leal, Manuel, Peraire, Joaquim, Portilla, Irene, Rodríguez-Gallego, Esther, Ruiz-Mateos, Ezequiel, Rull, Anna, Tarancon-Diez, Laura, Vidal, Francesc, Viladés, Consuelo   +12 more
core   +2 more sources