Results 41 to 50 of about 3,711,426 (256)
Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter [PDF]
FEBS Open BioThis minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Beccalli M, Bona B, Baldelli Bombelli F.
europepmc +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Structure and Charge States of the Selected Hydrogenated Silicon Clusters Si2-Si8 by Non-Conventional Tight-Binding Method [PDF]
Журнал нано- та електронної фізики, 2016 Structures of SinHm clusters in neutral, positive and double positive charge states have been calculated by nonconventional tight-binding method and molecular dynamics. An influence of the charge state and the termination by hydrogen of dangling bonds on
A.P. Mukhtarov +4 more
doaj +1 more source
, 2019 Recent progress in understanding the importance and origins of lipid rafts in microbial cell membranes has focused attention on membranes containing branched-chain fatty acids.
Jonathan D. Nickels (1367085) +3 more
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
BiologyThe remarkable conservation of soft tissues within Cambrian fossils has significantly enhanced our comprehension of the origins and evolutionary trajectories of animals, in addition to the progression of ecological intricacy.
Yue Liang +6 more
doaj +1 more source
Branched-Selective Hydroformylation of Nonactivated Olefins Using an N‑Triphos/Rh Catalyst
, 2018 We report a catalytic system comprised of nitrogen-centered di- or triphosphine ligands in conjunction with rhodium that is capable of delivering branched aldehydes from terminal olefin substrates which commonly give more linear aldehydes than branched ...
Kyoko Nozaki (1616881) +1 more
core +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Hyperbranched Silicone MDTQ Tack Promoters
Molecules, 2019 Low molecular weight, highly crosslinked silicone resins are widely used as reinforcing agents for highly transparent elastomers and adhesion/tack promoters in gels.
Sijia Zheng +3 more
doaj +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source