Results 51 to 60 of about 3,711,426 (256)

Structural basis of K11/K48-branched ubiquitin chain recognition by the human 26S proteasome

Nature Communications
Beyond the canonical K48-linked homotypic polyubiquitination for proteasome-targeted proteolysis, K11/K48-branched ubiquitin (Ub) chains are involved in fast-tracking protein turnover during cell cycle progression and proteotoxic stress.
Piotr Draczkowski, Szu-Ni Chen, Ting Chen, Yong-Sheng Wang, Hsin-An Shih, Jessica Y. C. Huang, Ming-Chieh Tsai, Shu-Yu Lin, Steven Lin, Rosa Viner, Yuan-Chih Chang, Kuen-Phon Wu, Shang-Te Danny Hsu   +12 more
doaj   +1 more source

Comparative analysis of natural rubber and isoprene rubber branched chain structures

Hecheng xiangjiao gongye
The branched chain structures of imported natural rubber RSS-1 and isoprene rubber molecular chains were compared and analyzed by nuclear magnetic resonance spectrometer.
LI Ze-chun1, QI Xing-guo1, XIANG Jian1, LIAO Shuang-quan2, YANG Chang-jin2
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

On-surface synthesis platform for highly branched oligomers based on sequential C—C coupling and C—H activation of carbenes

Nature Communications
On-surface synthesis is an emerging field for fabricating low-dimensional nanostructures. While carbenes are versatile reactive intermediates in solution-phase organic synthesis, they have rarely been explored in on-surface synthesis.
Yunjun Cao, Joel Mieres-Perez, Julien Frederic Rowen, Akshay Hemant Raut, Paul Schweer, Anran Bao, Wolfram Sander, Elsa Sanchez-Garcia, Karina Morgenstern   +8 more
doaj   +1 more source

Statistical polymer method: Modeling of macromolecules and aggregates with branching and crosslinking, formed in random processes

Discrete Dynamics in Nature and Society, 1998
The statistical polymer method is based on the consideration of averaged structures of all possible macromolecules of the same weight. One has derived equations allowing evaluation of all additive parameters of macromolecules and their systems.
Freddy A. Romm, Oleg L. Figovsky
doaj   +1 more source

Molar mass and solution conformation of branched alpha(1 - 4), alpha(1 - 6) Glucans. Part I: Glycogens in water [PDF]

, 2008
Solution molar masses and conformations of glycogens from different sources (rabbit, oyster, mussel and bovine) were analysed using sedimentation velocity in the analytical ultracentrifuge, size-exclusion chromatography coupled to multi-angle laser light
Schafer, B., Morris, Gordon, Ang, S., Lewis, S., Hill, S. E., Nobbmann, U., Harding, S. E.   +6 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Transport-generated signals uncover geometric features of evolving branched structures

Physical Review Research
Branched structures that evolve over time critically shape the function of diverse natural and engineered systems, from neuronal dendrites and vascular networks to pulmonary and root architectures.
Fabian H. Kreten, Ludger Santen, Reza Shaebani   +2 more
doaj   +1 more source

Some properties of approximants for branched continued fractions of the special form with positive and alternating-sign partial numerators

Karpatsʹkì Matematičnì Publìkacìï, 2018
The paper deals with research of convergence for one of the generalizations of continued fractions -- branched continued fractions of the special form with two branches.
T.M. Antonova, M.V. Dmytryshyn, S.M. Vozna   +2 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source