Results 51 to 60 of about 489,624 (317)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Branching Processes

open access: yesThe Annals of Mathematical Statistics, 1948
This paper is concerned with a simple mathematical model for a branching stochastic process. Using the language of family trees we may illustrate the process as follows. The probability that a man has exactly $r$ sons is $p_r, r = 0, 1, 2, \cdots$. Each of his sons (who together make up the first generation) has the same probabilities of having a given
openaire   +3 more sources

A note on multitype branching processes with immigration in a random environment

open access: yes, 2007
We consider a multitype branching process with immigration in a random environment introduced by Key in [Ann. Probab. 15 (1987) 344--353]. It was shown by Key that, under the assumptions made in [Ann. Probab. 15 (1987) 344--353], the branching process is
Roitershtein, Alexander
core   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Finite mixture models of superspreading in epidemics

open access: yesMathematical Biosciences and Engineering
Superspreading transmission is usually modeled using the negative binomial distribution, simply because its variance is larger than the mean and it can be long-tailed.
Suzanne M. O'Regan, John M. Drake
doaj   +1 more source

Bim Expression Modulates Branching Morphogenesis of the Epithelium and Endothelium

open access: yesBiomolecules, 2022
Branching morphogenesis is a key developmental process during organogenesis, such that its disruption frequently leads to long-term consequences.
Christine M. Sorenson   +6 more
doaj   +1 more source

Estimating the Propagation of Interdependent Cascading Outages with Multi-Type Branching Processes

open access: yes, 2016
In this paper, the multi-type branching process is applied to describe the statistics and interdependencies of line outages, the load shed, and isolated buses.
Ju, Wenyun, Qi, Junjian, Sun, Kai
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Turing mechanism underlying a branching model for lung morphogenesis. [PDF]

open access: yesPLoS ONE, 2017
The mammalian lung develops through branching morphogenesis. Two primary forms of branching, which occur in order, in the lung have been identified: tip bifurcation and side branching.
Hui Xu, Mingzhu Sun, Xin Zhao
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

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