Results 81 to 90 of about 913,345 (341)

Melatonin inhibits embryonic salivary gland branching morphogenesis by regulating both epithelial cell adhesion and morphology. [PDF]

open access: yesPLoS ONE, 2015
Many organs, including salivary glands, lung, and kidney, are formed by epithelial branching during embryonic development. Branching morphogenesis occurs via either local outgrowths or the formation of clefts that subdivide epithelia into buds.
Aya Obana-Koshino   +9 more
doaj   +1 more source

Identification of multitype branching processes [PDF]

open access: yesThe Annals of Statistics, 2000
We solve the problem of constructing an asymptotic global confidence region for the means and the covariance matrices of the reproduction distributions involved in a supercritical multitype branching process. Our approach is based on a central limit theorem associated with a quadratic law of large numbers performed by the maximum likelihood or the ...
Maaouia, F., Touati, A.
openaire   +6 more sources

Weibull-type limiting distribution for replicative systems

open access: yes, 2011
The Weibull function is widely used to describe skew distributions observed in nature. However, the origin of this ubiquity is not always obvious to explain.
Jean-Yves Fortin   +5 more
core   +1 more source

Branching random walks and multi-type contact-processes on the percolation cluster of ${\mathbb{Z}}^{d}$ [PDF]

open access: yes, 2015
In this paper we prove that, under the assumption of quasi-transitivity, if a branching random walk on ${{\mathbb{Z}}^d}$ survives locally (at arbitrarily large times there are individuals alive at the origin), then so does the same process when ...
Bertacchi, Daniela, Zucca, Fabio
core   +2 more sources

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Growth Velocities of Branched Actin Networks [PDF]

open access: yes, 2003
The growth of an actin network against an obstacle that stimulates branching locally is studied using several variants of a kinetic rate model based on the orientation-dependent number density of filaments. The model emphasizes the effects of branching and capping on the density of free filament ends.
arxiv   +1 more source

Branching processes for QuickCheck generators [PDF]

open access: yesACM SIGPLAN Notices, 2018
In QuickCheck (or, more generally, random testing), it is challenging to control random data generators' distributions---specially when it comes to user-defined algebraic data types (ADT). In this paper, we adapt results from an area of mathematics known as branching processes, and show how they help to analytically predict (at compile-time) the ...
John Hughes   +2 more
openaire   +4 more sources

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha   +6 more
wiley   +1 more source

Branch mode selection during early lung development. [PDF]

open access: yesPLoS Computational Biology, 2012
Many organs of higher organisms, such as the vascular system, lung, kidney, pancreas, liver and glands, are heavily branched structures. The branching process during lung development has been studied in great detail and is remarkably stereotyped.
Denis Menshykau   +2 more
doaj   +1 more source

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