Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Relationship Between Brand Presence and Emotions on Overall Acceptance and Purchase Intent of Commercial Chicken Noodle Soup. [PDF]
Loh DW, Parker A, Jefferies L.
europepmc +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Understanding perceived ride safety and trust formation in robotaxi services under day and night conditions. [PDF]
Liu Y, Li H, Pan Y.
europepmc +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Effort or ease: the impact of sharing self-improvement vs. hedonic behaviors on personal brand evaluation. [PDF]
Ruan C, Zhang X, Zhuo F, Lu Z, Li J.
europepmc +1 more source
Strategic options for retailers for branding private label portfolios
Diederich Bakker
openalex +1 more source
Fluoro-forest: a random forest workflow for cell type annotation in high-dimensional immunofluorescence imaging with limited training data. [PDF]
Brand J, Zhang W, Carchman E, Dinh HQ.
europepmc +1 more source
GP Consultations for Venous Thromboembolism (VTE) After mRNA and Adeno-Vector-Based COVID-19 Vaccination-An Exposure-Anchored Self-Controlled Cohort Study Based on Primary Healthcare Data From the Netherlands. [PDF]
Jajou R +6 more
europepmc +1 more source

