Results 91 to 100 of about 386,927 (307)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Spontaneity vs. suppression: Differential impacts of platform types on user value co-creation behavior in online brand communities

open access: yesActa Psychologica
User participation in value co-creation is a crucial guarantee for the successful operation of online brand communities. Based on the Cognition-Affect-Conation (C-A-C) theoretical framework, this study constructs a theoretical model of the influencing ...
Chengyi Le   +3 more
doaj   +1 more source

LAND [R]EVOLUTION – THE CELLULAR SYSTEM MODEL; PLATAFORMA DE ACTIVAÇÃO DOS TERRITÓRIOS [PDF]

open access: yes, 2011
RESUMO Segundo Kotler (2010) a co-criação e co-participação continuada permite às marcas uma grande aproximação com os seus clientes, pois esta plataforma facilita na criação de insights e na difusão da mensagem da marca, melhor que no processo ...
Mateus, Américo   +2 more
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Branding sustainability : opportunity and risk behind a brand-based approach to sustainable markets [PDF]

open access: yes, 2014
ephemera works with a Creative Commons Licence, which allows others to copy, distribute and transmit the work, so long as the work is attributed to the author(s).
Halliday, Sue, Lehner, Matthias
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Advertising co-creation and the engagement factor [PDF]

open access: yes, 2013
In 2009, McDonald's launched a new interactive sign at Picadilly Circus, one of the most visited places in London. There, passers-by could interact with moving images displayed on McDonald's giant LED screen.
Balonas, Sara, Melo, Ana Duarte
core  

Weird Science! It’s My Creation . . . Is It Really? Or: Crafting a New Universal Trademark Standard for User-Created Avatars [PDF]

open access: yes, 2018
In modern trademark law the process of registering a valid trademark is straightforward. In the United States the Lanham Act is the ruling law of trademark law.
Esparza, Ryan
core   +2 more sources

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