Results 121 to 130 of about 386,927 (307)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Building Apartment Developer Satisfaction with Brand Image, Value Co-Creation and Supply Chain Agility along with its Impact on Developer Loyalty Towards Apartment Contractors

IJEBD (International Journal of Entrepreneurship and Business Development)
Objective: Apartment sector is one of the important real estate sectors of a country. The aim of this research is to analyse the influence of brand image, value co-creation, and supply chain agility on customer satisfaction and its impact on developer ...
Augustinus Setijanto, Sarwono Hardjomuljadi, Hendrik Sulistio   +2 more
doaj   +1 more source

From ‘Spiral Scratch’ to PledgeMusic: The Birth & Rebirth of Punk Culture’s Entrepreneurial Spirit [PDF]

, 2017
Punk has come a long way from its prematurely declared death in the early-1980s to being not-so-dead after all in the 1990s to still being ‘alive, loud and kicking' today.
Wohlfeil, Markus
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Analyzing The Serial Mediation of Customer Brand Co-Creation Behavior and Perceived Value in Enhancing Revisit Intention

Jurnal Aplikasi Manajemen
The café industry faces increasing competition, particularly in attracting and retaining Generation Z customers who prioritize unique experiences and emotional connections.
Ni Made Purnami, NI Wayan Mujiati, Uswatun Siwi Kartika Sari, Desak Komang Dea Marcellina Putri Darmadi, Carla Alexandra De Jesus Da Costa   +4 more
doaj   +1 more source

Design and radical innovation: a strategic perspective based upon a comparative case study between emergent and traditional industries in Portugal [PDF]

, 2005
The survival challenge faced by the Portuguese companies nowadays has promoted Innovation as the main management strategy to be applied. This research reveals the importance and the role of Design as the basic and integrative tool for the success of ...
Brândao, Elísio (Coordinador), Díez de Castro, Enrique Carlos (Coordinador), Mateus, Américo, Sousa, António João de   +3 more
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Value Co-destruction: The Dark Side of Interactions in Online Brand Communities

SAGE Open
With the advent of online communities, firms have invested heavily in creating their brand communities as a value co-creation platform to engage with their customers. However, customer interactions in online brand communities may not always be beneficial
Jia Luo, Jiayu Wang, Rui Liu, Kaigeng Li
doaj   +1 more source

Born Globals and Brand Co-Creation : The Stakeholder’s Role in Brand Co-Creation of Born Globals in Germany

, 2021
Master's thesis in Business administration (BE501)
openaire   +1 more source