Results 111 to 120 of about 521,689 (353)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Research on the marketing strategy of dynamic brand management in the digital transformation of Baijiu [PDF]

Zhongguo niangzao
Under the development background of globalization advancement and technological innovation, the rapid changes in the modern market environment have posed new challenges to traditional brand management strategies, which are difficult to adapt to the ...
WANG Zhentao, HUANG Tingxue, ZHANG Quan
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Brand and customer management mindsets creating brand relationships and equity in young adults

South African Journal of Business Management
Purpose: Players in the highly competitive smartphone industry can use either brand management mindset (BMM) or customer management mindset (CMM) to build consumer-brand relationships and ultimate customer-based brand equity (CBBE) in different market ...
Chuma Diniso, Helen I. Duh
doaj   +1 more source

Revenue Management at the Hong Kong Grand: The Dine in Grandeur Dilemma [PDF]

, 2009
This case provides an interesting example of the trade-offs between revenue management, brand image, loyalty programs, and employee satisfaction. The Dine In Grandeur Program (DIG) is financially successful (see the discussion below), but might be ...
Hart, Christopher W., Kimes, Sheryl E., Verma, Rohit   +2 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Assessing the relationship between brand message and guests’ choice in the Sarova hotel chain in Nairobi

Mенаџмент у хотелијерству и туризму, 2019
Hotels and restaurants in Kenya aim to distinguish their brand image and differentiate their product or service from competitors by implementing particular brand approaches.
Mwalimu Zipporah, Stephen Macharia, Judy Kibe   +2 more
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Elevating Educational Quality: A Management Strategy to Enhancing Muhammadiyah School Branding [PDF]

, 2023
Istikomah Istikomah
openalex   +1 more source

A Review of CEM: Customer Engagement as Innovation Co-Creator [PDF]

, 2013
Competition is very tight causing companies looking for a competitive edge, both in the product packaging and in maintaining good relations with their customers. The management of good relationship is commonly referred to Customer Relationship Management
Elidjen, E. (Elidjen)
core