Results 201 to 210 of about 1,040,105 (296)

Advancing Biotherapeutic Treatment of Ulcerative Colitis Using Lipid Mesophases: Formulation Design and Preclinical Validation

Advanced Science, EarlyView.
Lipid mesophases provide a versatile platform for colon‐targeted delivery of biotherapeutics, protecting them from degradation while enhancing mucoadhesion and enabling localized, controlled release to the inflamed mucosa after oral or rectal administration. In a DSS‐induced colitis model, this strategy reduced disease activity, inflammatory biomarkers,
Rafaela Gazzi, Tiziana Cremona, Reto Czekalla, Emily Campbell, Marlene Schwarzfischer, Doris Pöhlmann, Vanessa Dobernig, Gerhard Rogler, Michael Scharl, Alessandra Bergadano, Raffaele Mezzenga, Martin Kuentz, Paola Luciani, Simone Aleandri   +13 more
wiley   +1 more source

Person, Affective, Cognitive, and Executive Dimensions Associated with Problematic Social Media Use, Internet Gaming Disorder, and Their Co-Occurrence in Young Adults. [PDF]

Eur J Investig Health Psychol Educ
León-Méndez M, Padrón I, Fumero A, Perestelo-Pérez L, Marrero RJ.   +4 more
europepmc   +1 more source

Aged ZnO Nanoparticles Promote Breast Cancer Lung Metastasis by Remodeling the Pulmonary Microenvironment Through the CXCL10/Wnt/β‐Catenin Axis

Advanced Science, EarlyView.
In summary, pulmonary exposure to ZnO NPs, particularly aged NPs, promotes breast cancer metastasis by remodelling the lung tumour microenvironment. Aged ZnO NPs enrich M2‐macrophages, MDSCs and activated CAFs to form an immunosuppressive metastatic niche. CXCL10 from these cells drives metastasis via Wnt/β‐catenin activation.
Yong Zhu, Siyu Wang, Tong Lin, Jingyi Zhang, Jingya Yang, Dixiang Kang, Wenting Zhao, Na Yu, Meimei Wang   +8 more
wiley   +1 more source

Moral Disengagement and Unethical Generative AI Use as the Chain Mediators Between Antagonistic Personality and Problematic Generative AI Use. [PDF]

Behav Sci (Basel)
Kırcaburun K, Özdemir P.
europepmc   +1 more source

Activation‐Induced Turbostratic Ordering in pDCPD‐Derived Hard Carbon Enables Stable Carbonate‐Based Sodium‐Ion Storage

Advanced Science, EarlyView.
Hard carbon derived from templated poly(dicyclopentadiene) as anode for sodium–ion batteries was engineered through carbonization and second‐step CO2${\rm CO}_2$ activation. High‐temperature carbonization and activation increased local ordering while reducing defects without inducing structural fracture.
David Schuster, Glen J. Smales, Max Schmallegger, Julian M Rosalie, Konstantin Kraushaar, Andreas Lißner, Julia Bohdal, Pia Winter, Bernd Fuchsbichler, Stefan Koller, Sebastijan Kovačič, Christian Slugovc   +11 more
wiley   +1 more source

Influence of sponsorship on betting intentions: from linear to deep learning models. [PDF]

Harm Reduct J
Alonso Dos Santos M, Fuentes-Solis R, Gómez-Tafalla AM, Torres-Moraga E.   +3 more
europepmc   +1 more source

Fuyuan Huoxue Decoction Promotes Lumbar Interbody Fusion in Rats: Role of Macrophage‐Driven Inflammation and the TLR9/NF‐κB Pathway

Advanced Science, EarlyView.
Fuyuan Huoxue decoction improves lumbar interbody fusion in rats while reducing inflammatory macrophage activity and supporting bone‐forming stem cells. Experiments implicate extracellular DNA and TLR9/NF‐κB signaling in early responses. These findings point to coordinated control of inflammation and osteogenesis as a potential route to stronger spinal
Hongwei Gao, Han Wu, Shaorong Li, Weijian Wang, Yijian Guo, Shuai Cheng, Jiayi Sun, Jilong An, Wei Zhang   +8 more
wiley   +1 more source

To Buy or Not to Buy Under Brand Image Transgression? Consumer Behavior and Underlying Mechanisms from a Power Distance Belief Perspective. [PDF]

Behav Sci (Basel)
Zhang L, Shi B.
europepmc   +1 more source

Multifunctional Matrix‐Activated Electrodes Enabling Efficient Proton Transport and Durable Low‐Pt Operation for High‐Temperature Proton Exchange Membrane Fuel Cells

Advanced Energy Materials, EarlyView.
This work introduces a CeHP‐enabled multifunctional matrix‐activated electrode (MME) for high‐temperature PEM fuel cells, forming an electrochemically and mechanically functional matrix within the catalyst layer. The design increases peak power density by 38% and reduces voltage decay by 62% at 240 °C, while using only 40% of the Pt loading of a ...
Gyeongseok Gwak, Sunjin Park, Joonbyum Kim, Hena Lee, Jihyeon Ok, Chae Young Lee, JunHwa Kwon, Jong Geun Seong, Sung Pil Yoon, Suk‐Woo Nam, Hansung Kim, Katie Heeyum Lim, So Young Lee   +12 more
wiley   +1 more source

How Perceived Crowding Shapes Tourists' Impulsive Buying in Internet-Famous Supermarkets: The Roles of Bipolar Emotions and Brand Trust. [PDF]

Behav Sci (Basel)
Lu Y, Zhang X, Xiao Y, Liu D, Xi J.
europepmc   +1 more source