Results 201 to 210 of about 33,569 (238)

Management of Women With BRCA Mutations

JAMA, 2011
Ms E, a 41-year-old BRCA1 mutation carrier, was diagnosed 4 years ago as having breast cancer and opted for breast-conserving therapy. Prior to receiving chemotherapy, she harvested her eggs through in vitro fertilization and subsequently used preimplantation genetic diagnosis; 3 months ago she delivered a healthy boy.
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When the BRCA test is negative—Prevention strategies in women who have no detectable mutation (BRCA-) compared to women harboring positive BRCA mutations (BRCA+)

Journal of Clinical Oncology, 2008
1534 Background: Much attention has been focused on screening and risk reduction, including prophylactic mastectomy (PM) or oophorectomy (PO) in BRCA+ mutation carriers (Rebbeck 1999, Eisen 2005, Kauff 2007). In families with a known BRCA mutation (BRCA+) or a history of hereditary breast cancer (BC) or ovarian cancer (OC), relatives in whom a mutation
S. Verma, S. F. Dent, L. Paquet, L. Bitonti   +3 more
openaire   +1 more source

Comparison of Nodal Metastasis Between BRCA Mutation Carriers and Non-BRCA Mutation Carriers with Breast Cancer

Annals of Surgical Oncology, 2014
This study evaluates whether nodal status differs between breast cancer patients with BRCA mutations and those confirmed not to harbor mutations.A prospective database identified patients with breast cancer who underwent genetic testing and axillary staging.
Shahrbanoo F, Noori, Alexandra, Gangi, Maria E, Nelson, Michael, Choi, Parisa, Mirzadehgan, Alison K, Bonk, James, Mirocha, Farin, Amersi, Armando E, Giuliano   +8 more
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Progress in BRCA -Mutated Ovarian Cancer

New England Journal of Medicine, 2018
The article by Moore et al.1 in this issue of the Journal is the culmination of a long march for olaparib in the treatment of BRCA-mutated high-grade serous ovarian cancer — one that began with its...
David R, Spriggs, Dan L, Longo
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Targeting BRCA-mutated tumors in mitosis

Nature Cancer, 2021
Demis Menolfi, Shan Zha
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A Meta-Analysis of Reversion Mutations in BRCA Genes Identifies Signatures of DNA End-Joining Repair Mechanisms Driving Therapy Resistance

Annals of Oncology, 2021
M J O'Connor
exaly  

BRCA Mutation

2012
Ashley N. Hardy, Elizabeth Tarasewicz, Jacqueline S. Jeruss   +2 more
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Obesity as a promoter in BRCA mutation carriers

Nature Reviews Cancer, 2023
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Emergence of BRCA Reversion Mutations in Patients With Metastatic Castration-Resistant Prostate Cancer After Treatment With Rucaparib

European Urology, 2023
Gurkamal Chatta, Albert Font
exaly  

BRCA Gene Mutations and Cancer

AJN, American Journal of Nursing, 2002
openaire   +2 more sources