Results 31 to 40 of about 739,269 (304)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Study of jet precession, recirculation and vortex breakdown in turbulent swirling jets using LES. [PDF]
, 2009 Large eddy simulations (LES) are used to investigate turbulent isothermal swirling flows with a strong emphasis on vortex breakdown, recirculation and instability behaviour.
Ranga Dinesh, K.K.J. +3 more
core +1 more source
Effect of Frequency on Degradation in BOPP Films Under Repetitively Pulsed Voltage
CSEE Journal of Power and Energy SystemsOperating conditions of film capacitors are complex, and the problem of film insulation failure caused by repetitively pulsed voltage is becoming ever serious.
Chuansheng Zhang +5 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Laser-induced breakdown of an optically trapped gold nanoparticle for single cell transfection [PDF]
, 2013 The cell selective introduction of therapeutic agents remains a challenging problem. Here we demonstrate spatially controlled cavitation instigated by laser-induced breakdown of an optically trapped single gold nanoparticle of diameter 100 nm. The energy
Gunn-Moore, Frank J +12 more
core +1 more source
Characteristics Comparison of SiC and GaN Extrinsic Vertical Photoconductive Switches
IEEE Journal of the Electron Devices SocietyVertical extrinsic photoconductive semiconductor switches (PCSSs) are presented with initial characteristics comparison between V-doped 4H-SiC and Fe-doped GaN PCSS under axial triggering such as dark resistance, photoconductivity, power output, and ...
Linglong Zeng +9 more
doaj +1 more source
Restarting from Specific Points to Cure Breakdown in Lanczos-type Algorithms
Journal of Mathematical and Fundamental Sciences, 2015 Breakdown in Lanczos-type algorithms is a common phenomenon which is due to the non-existence of some orthogonal polynomials. It causes the solution process to halt.
Maharani, Abdellah Salhi
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Combustion applications of laser-induced breakdown spectroscopy
, 2020 The laser-induced breakdown spectroscopy (LIBS) technique has the capability to perform multielemental, remote, online, in situ analysis with no/minimum sample preparations. LIBS has created a great deal of interest in combustion diagnostic research.
Fang Y. Yueh +9 more
core +1 more source