Results 51 to 60 of about 739,269 (304)

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Breakdown points for maximum likelihood estimators of location-scale mixtures [PDF]

open access: yes, 2004
ML-estimation based on mixtures of Normal distributions is a widely used tool for cluster analysis. However, a single outlier can make the parameter estimation of at least one of the mixture components break down. Among others, the estimation of mixtures
Hennig, C, Hennig C
core   +1 more source

Using Modeling and Simulation to Study the Influence of TiO2 Shape on the Dielectric Properties of TiO2/PVDF Composite

open access: yesJournal of Harbin University of Science and Technology, 2022
TiO2/PVDF composite materials have excellent high dielectric properties and have wide application prospects in the fields of high voltage and energy storage insulation.In this paper, the finite element method was used to simulate the structure and ...
SHAN Xue-wen, YIN Jing-hua
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Short-term Breakdown and Long-term Failure in Nanodielectrics: A Review [PDF]

open access: yes, 2010
Nanodielectrics, which are concentrated in polymer matrix incorporating nanofillers, have received considerable attention due to their potential benefits as dielectrics.
Li, Shengtao   +7 more
core   +2 more sources

Experimental research of ECW pre-ionization and assisted startup in EAST

open access: yesNuclear Fusion
Experimental research on the electron cyclotron wave (ECW) pre-ionization and assisted start-up was carried out systematically for the first time in EAST tokamak, which is a superconducting device with ITER-like full metal wall.
Runze Chen   +24 more
doaj   +1 more source

Breakdowns [PDF]

open access: yesSSRN Electronic Journal, 2012
We study a continuous-time game of strategic experimentation in which the players try to assess the failure rate of some new equipment or technology. Breakdowns occur at the jump times of a Poisson process whose unknown intensity is either high or low.
Keller, Godfrey, Rady, Sven
openaire   +6 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Space charge and its impact on DC breakdown of polymeric materials

open access: yes, 2013
The presence of space charge will lead to distortion of electric field distribution within the dielectric material, resulting electric field enhancement in certain region of the dielectric. The electric field enhancement could cause material degradation,
Chen, George
core   +1 more source

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