Results 51 to 60 of about 477,993 (266)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Formation of field-induced breakdown precursors on metallic electrode surfaces

open access: yesFrontiers in Physics
Understanding the underlying factors responsible for higher-than-anticipated local field enhancements required to trigger vacuum breakdown on pristine metal surfaces is crucial for the development of devices capable of withstanding intense operational ...
Soumendu Bagchi   +2 more
doaj   +1 more source

Analysis of single server repairable queueing system with many kinds of service, single working vacation and standby server [PDF]

open access: yesYugoslav Journal of Operations Research
We consider a single server queueing model in which the customers arrive according to a Markovian Arrival Process (MAP). We modeled this queueing system with many kinds of service where the customers can choose any kind from the server.
Baby Saroja K., Suvitha V.
doaj   +1 more source

Anarchy and its Breakdown [PDF]

open access: yesJournal of Political Economy, 1995
Anarchy, defined as a system in which participants can seize and defend resources without regulation from above, is not chaos but rather a spontaneous order. However, anarchy is fragile and may dissolve either into formless "amorphy" or into a more organized system such as hierarchy.
openaire   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Experimental Study on the Discharge Characteristics of a Dripping ‘Rod–Plane’ Air Gap at High Altitude Under DC Voltages

open access: yesEnergies
High-voltage transmission and substation projects at high altitudes are pivotal in realizing the objective of universal electricity access. However, the reduced air density at elevated heights facilitates the formation and propagation of discharges ...
Chuyan Zhang   +5 more
doaj   +1 more source

Breakdown of Coherence ?

open access: yes, 2007
10 pages, Talk given at 12th International Conference on Elastic and Diffractive Scattering (EDS '07), May 21st-25th 2007, DESY ...
openaire   +3 more sources

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

Deep Neural Network Using Transfer Learning Technique for MOSFETs With Different Gate Lengths in Avalanche Region

open access: yesIEEE Access
In this paper, a transfer learning technique was first utilized to obtain deep neural network models for different gate lengths in the avalanche breakdown regime. Once the characteristics of a gate-length metal-oxide-semiconductor field-effect transistor
Chie-In Lee   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy