Results 41 to 50 of about 460,117 (237)

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Experimental research of ECW pre-ionization and assisted startup in EAST

Nuclear Fusion
Experimental research on the electron cyclotron wave (ECW) pre-ionization and assisted start-up was carried out systematically for the first time in EAST tokamak, which is a superconducting device with ITER-like full metal wall.
Runze Chen, Wenbin Liu, Jinping Qian, Bin Zhang, Hongjuan Sun, Zhengping Luo, Yaowei Yu, Wei Gao, Miaohui Li, Handong Xu, Mao Wang, Guizhong Zuo, Ling Zhang, Ruijie Zhou, Tianqi Jia, Pan Li, Wei Wang, Yifan He, Zuhao Wang, Ye Tao, Yunchan Hu, Zhongfang Guan, Wenyi Lu, Yutong Guo, Xianzu Gong   +24 more
doaj   +1 more source

Efeito das condições de atmosfera controlada sobre a ocorrência de degenerescência em maçã 'Fuji' Effect of controlled atmosphere conditions on the breakdown of 'Fuji' apples

Scientia Agricola, 1995
O trabalho foi conduzido durante o ano de 1993, com objetivo avaliar o efeito das temperaturas e concentrações de oxigênio nas câmaras de atmosfera controlada (AC), sobre a manifestação da degenerescência e conservação da qualidade dos frutos da maçã ...
A. Brackmann, A.A. Saquet
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Impact of Electrode Distance in a Quasi-Uniform Model Electrode System on Lightning Impulse Breakdown Voltage in Various Insulating Liquids

Energies
This study presents findings on the influence of gap length distance on the lightning impulse breakdown voltage of three dielectric liquids of different chemical origins.
Wiktor Kunikowski, Pawel Rozga, Bartlomiej Pasternak, Jakub Staniewski, Filip Stuchala, Konrad Strzelecki   +5 more
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Formation of field-induced breakdown precursors on metallic electrode surfaces

Frontiers in Physics
Understanding the underlying factors responsible for higher-than-anticipated local field enhancements required to trigger vacuum breakdown on pristine metal surfaces is crucial for the development of devices capable of withstanding intense operational ...
Soumendu Bagchi, Evgenya Simakov, Danny Perez   +2 more
doaj   +1 more source