Results 31 to 40 of about 217,160 (249)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Pre-breakdown characteristics of contaminated power transformer oil [PDF]

2007 Annual Report - Conference on Electrical Insulation and Dielectric Phenomena, 2007
In this paper we have studied pre-breakdown characteristics of transformer oil in the presence of different levels of contamination. The contaminant is fibrous dust from pressboard insulation used for high voltage transformers. The contamination level investigated in the present study ranges from 0.0025 to 0.0075% by weight.
Chen, G, Zuber, H M
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Study on Breakdown Characteristics of On-Train High-Voltage Combined Electrical Apparatus Under Lightning Transient Conditions

Applied Sciences
The high-voltage system of high-speed trains is now in the form of combined electrical apparatus, which has a high probability of insulation breakdown due to frequent overvoltage during operation.
Jixing Sun, Kun Zhang, Yide Liu, Sile Yang, Jiuding Tan   +4 more
doaj   +1 more source

Significantly Improved Electrical Breakdown Strength of Natural Ester Liquid Dielectrics by Doping Ultraviolet Absorbing Molecules

IEEE Access, 2019
In this paper, we experimentally demonstrate that molecules with maximum absorption wavelength corresponding to the first excitation energy of base liquid molecules are able to significantly improve the electrical performances of natural ester oils.
Suning Liang, Feipeng Wang, Zhengyong Huang, Weigen Chen, Youyuan Wang, Jian Li   +5 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Effect of Thickness on the Breakdown Characteristics of Organic Insulation Materials under Microsecond Pulse Voltage

Energies
Thickness affects the electrical breakdown strength (EBD) of insulation materials, and the variation of EBD with thickness (d) is an important basis for insulation design.
Xudong Li, Xin Liu, Jiasheng Ru, Zhibin Zeng, Haoran Bian, Yuefang Li, Hua Zhong, Lei Chen   +7 more
doaj   +1 more source

Bubble deformation in the repetitive pulsed glycerin pulse forming line and its relation with the liquid breakdown

AIP Advances, 2019
Glycerin is a promising liquid dielectric for pulsed power systems because of its high storage energy density and high resistivity. In order to further improve the energy storage density of glycerin, its breakdown characteristics should be investigated ...
Xiao Yang, Jian-Hua Yang, Xin-Bing Cheng, Jiu-Yuan Geng, Bao-Liang Qian   +4 more
doaj   +1 more source

Numerical Prediction of DC Breakdown Characteristics in LDPE With Current Profile as Critical Index

IEEE Access, 2020
Understanding the DC breakdown characteristics of polymeric insulators is essential for stable operation of high-capacity DC electrical equipment.
Minhee Kim, Su-Hun Kim, Se-Hee Lee
doaj   +1 more source

Partial discharge breakdown characteristics under needle–plate defect configuration

AIP Advances, 2021
Partial discharge of the dielectric is an important problem in fault detection of transmission line systems. It has gained gigantic attention to understand the breakdown characteristics of partial discharge.
Dandan Zou, Hanyu Pan, M. Hasnain Qaisrani   +2 more
doaj   +1 more source