Results 71 to 80 of about 255,891 (299)

Highly Efficient Estimators of Multivariate Location with High Breakdown Point [PDF]

open access: yes, 1991
We propose an affine equivariant estimator of multivariate location that combines a high breakdown point and a bounded influence function with high asymptotic efficiency.
Lopuhaa, H.P. (author), Lopuhaa, H.P.
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Breakdown of the Perturbative Renormalization Group at Certain Quantum Critical Points [PDF]

open access: yesPhysical Review Letters, 2004
It is shown that the presence of multiple time scales at a quantum critical point can lead to a breakdown of the loop expansion for critical exponents, since coefficients in the expansion diverge. Consequently, results obtained from finite-order perturbative renormalization-group treatments may be not be an approximation in any sense to the true ...
Belitz, D.   +2 more
openaire   +3 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Percolating model of gas breakdown

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2007
We consider the existing models of electrical breakdown. Using the theory of overflow to analyze the ionized overlap of gas space is suggested. The condition of spark breakdown of gas-discharge space for any field structure is defined based on the point ...
H. D. Lamazhapov
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

TIME-DEPENDENT DIELECTRIC BREAKDOWN CHARACTERIZATION OF A HIGH VOLTAGE CAPACITOR [PDF]

open access: yes, 2011
NXP Semiconductors Business Unit (BU) Automotive is a corporate organization that provides design technology for the automotive product creation process.
Sasongko, Brecia Nurastu
core  

The Influence Functions and Breakdown Points of the L-Moments, Tl-Moments and the LQ-Moments Estimators [PDF]

open access: yesThe Egyptian Statistical Journal, 2011
The L-moments are defined as linear combinations of expected values of order statistics of an absolutely continuous random variable, (Hosking 1990).
Osama Abd Elaziz Hussien
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

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