Results 41 to 50 of about 215,040 (353)

Study on breakdown characteristics of nano-modified transformer oil at low temperature

open access: yesEnergy Reports, 2023
Studying the breakdown characteristics of nano-modified transformer oil at low temperature is helpful to improve the breakdown voltage of transformer oil at low temperature.
Chunxu Qin   +4 more
doaj  

Influence of Space Charge on Dielectric Property and Breakdown Strength of Polypropylene Dielectrics under Strong Electric Field

open access: yesEnergies, 2022
Space charge accumulation in polypropylene (PP) affect the dielectric properties and breakdown strength of the material. The pre-injected charge in PP under the action of different polarity voltage is quantitatively characterized, and the effects of the ...
Zhaoliang Xing   +6 more
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Meandering gate edges for breakdown voltage enhancement in AlGaN/GaN HEMTs

open access: yes, 2019
In this letter, we report on a unique device design strategy for increasing the breakdown voltage and hence Baliga Figure of Merit (BFOM) of III-nitride HEMTs by engineering the gate edge towards the drain.
Dolmanan, Surani B.   +4 more
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

DC Breakdown Voltage of Synthetic Ester Liquid-Based Nanofluids

open access: yesIEEE Access, 2020
Synthetic esters are potential substitutes for mineral oil in power transformers owing to their biodegradability and excellent dielectric withstand. Furthermore, the addition of certain nanoparticles improves the cooling property of liquids.
Abderrahmane Beroual   +2 more
doaj   +1 more source

Numerical simulation study of rock breaking mechanism by high voltage electric pulse

open access: yes矿业科学学报, 2023
High-voltage electric pulse(HVEP)drilling has become a new and efficient rock breaking method, which is also the research focus in the field of drilling speed increase.
Liu Weiji   +3 more
doaj   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

open access: yesFEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji   +3 more
wiley   +1 more source

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