Results 61 to 70 of about 982,593 (292)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

2 kV Al0.64Ga0.36N-channel high electron mobility transistors with passivation and field plates

Applied Physics Express
High voltage (∼2 kV) Al _0.64 Ga _0.36 N-channel high electron mobility transistors were fabricated with an on-resistance of ∼75 Ω. mm (∼21 mΩ. cm ^2 ). Two field plates of variable dimensions were utilized to optimize the breakdown voltage.
Md Tahmidul Alam, Jiahao Chen, Kenneth Stephenson, Md Abdullah-Al Mamun, Abdullah Al Mamun Mazumder, Shubhra S. Pasayat, Asif Khan, Chirag Gupta   +7 more
doaj   +1 more source

Partial Discharge Inception and Breakdown Voltage Analysis in PCB-Based Electrode Structures

Applied Sciences
This paper investigates partial discharge (PD) characteristics and breakdown behavior in five electrode configurations fabricated from fiberglass circuit boards, including parallel electrode (PE), triangular electrode (TE), right-angled electrode (RE ...
Tzu-Ching Tai, Shiao-Yu Andrew Bao, Bharath Kumar Boyanapalli, Cheng-Chien Kuo, Chien-Kuo Chang   +4 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Comparative Study of Breakdown Voltage of Mineral, Synthetic and Natural Oils and Based Mineral Oil Mixtures under AC and DC Voltages

Energies, 2017
This paper deals with a comparative study of AC and DC breakdown voltages of based mineral oil mixtures with natural and synthetic esters mainly used in high voltage power transformers.
Abderrahmane Beroual, Usama Khaled, Phanuel Seraphine Mbolo Noah, Henry Sitorus   +3 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Study on the influence of O2 on the breakdown voltage and self-recovery characteristics of c-C4F8/N2 mixture

AIP Advances, 2018
The c-C4F8 gas is considered to have great potential as a gaseous medium for use in gas-insulated equipment due to its good insulation properties and its relatively low greenhouse gas potential (Global warming potential, GWP) relative to SF6.
Song Xiao, Shuangshuang Tian, Yann Cressault, Xiaoxing Zhang, Ju Tang, Yi Li, Zaitao Deng   +6 more
doaj   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Optical fiber imaging for high speed plasma motion diagnostics: applied to low voltage circuit breakers [PDF]

, 2010
An integrated portable measurement system is described for the study of high speed and high temperature unsteady plasma flows such as those found in the vicinity of high current switching arcs.
Tribulato, G., Cross, K.J., A. Balestrero, J. W. McBride, G. Tribulato, K. J. Cross, L. Ghezzi, McBride, J.W., Balestrero, A., Ghezzi, L.   +9 more
core   +1 more source