Results 41 to 50 of about 49,704 (264)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

The Investigation of Field Plate Design in 500 V High Voltage NLDMOS

open access: yesAdvances in Condensed Matter Physics, 2015
This paper presents a 500 V high voltage NLDMOS with breakdown voltage (VBD) improved by field plate technology. Effect of metal field plate (MFP) and polysilicon field plate (PFP) on breakdown voltage improvement of high voltage NLDMOS is studied.
Donghua Liu   +10 more
doaj   +1 more source

DC Breakdown Voltage of Synthetic Ester Liquid-Based Nanofluids

open access: yesIEEE Access, 2020
Synthetic esters are potential substitutes for mineral oil in power transformers owing to their biodegradability and excellent dielectric withstand. Furthermore, the addition of certain nanoparticles improves the cooling property of liquids.
Abderrahmane Beroual   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Study of Parameters Affecting Breakdown Voltage of Bipolar Static Induction Transistor

open access: yesИзвестия высших учебных заведений России: Радиоэлектроника, 2017
The article considers structural and technological parameters affecting breakdown voltage of a BSIT transistor cell. The main objective of the scientific research in that field is optimization of manufacturing techniques of power electronics transistor ...
T. A. Ismailov   +2 more
doaj  

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Comparison of AC breakdown characteristics on insulation paper (pressboard) immersed by three-element mixed insulation oil and mineral oil

open access: yesHigh Voltage, 2019
Insulation oil is an important dielectric in power devices, and many studies on mixed insulation oil have been conducted in recent years to improve the performance of insulation oils.
Dawei Feng   +5 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Partial Discharge Inception and Breakdown Voltage Analysis in PCB-Based Electrode Structures

open access: yesApplied Sciences
This paper investigates partial discharge (PD) characteristics and breakdown behavior in five electrode configurations fabricated from fiberglass circuit boards, including parallel electrode (PE), triangular electrode (TE), right-angled electrode (RE ...
Tzu-Ching Tai   +4 more
doaj   +1 more source

Study of the breakdown voltage of SiPMs [PDF]

open access: yesNuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2017
7 pages, 1 table, 7 ...
Chmill, V.   +4 more
openaire   +2 more sources

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