Results 71 to 80 of about 65,483 (305)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
High Voltage, 2019 Insulation oil is an important dielectric in power devices, and many studies on mixed insulation oil have been conducted in recent years to improve the performance of insulation oils.
Dawei Feng +5 more
doaj +1 more source
Field Analysis of SF(6) Gas Insulated Cables and Its Application to Spacer Design
, 1974 This paper describes the spacer design for SF(6) gas insulated cables. The maximum electric stress within the cable is calculated by a numerical method, and it is recognized that the breakdown voltage depends linearly on the calculated values.
Yamamoto, Hideki +2 more
core +1 more source
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Study of the breakdown voltage of SiPMs [PDF]
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2017 7 pages, 1 table, 7 ...
Chmill, V. +4 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Partial Discharge Inception and Breakdown Voltage Analysis in PCB-Based Electrode Structures
Applied SciencesThis paper investigates partial discharge (PD) characteristics and breakdown behavior in five electrode configurations fabricated from fiberglass circuit boards, including parallel electrode (PE), triangular electrode (TE), right-angled electrode (RE ...
Tzu-Ching Tai +4 more
doaj +1 more source
Charge Accumulation on Slightly Conductive Barrier Systems and Its Effect on Breakdown Voltage in an Air Insulated Rod Plane Arrangement [PDF]
, 2019 The barrier effect has been known since the 1930's. It is of great importance in the field of high voltage engineering as the breakdown voltage of an electrode arrangement can be increased significantly when dielectric barriers are applied. Nevertheless,
A. Blaszczyk +11 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source