Results 41 to 50 of about 81,828 (263)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Breaking Wave Forces on a Large Diameter Cell
Experiments have been carried out by using non-breaking waves and breaking waves to investigate the wave forces on a vertical circular cell located in the shallow water. Based on the experimental data, the drag coefficient and the inertia coefficient of a circular cylinder and the curling factor of breaking waves are estimated, and the computation ...
Akira Watanbe, Kiyoshi Horikawa
openaire +2 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
High-density planting has significantly boosted maize yields in Xinjiang China. However, excessive nitrogen application under such conditions has intensified stem lodging risks, revealing inconsistencies between conventional nitrogen fertilization ...
Juan Zhai +9 more
doaj +1 more source
The interactions among agar, gellan gum, gelatin, and modified waxy corn starch in the formation of mixed gels were examined in five different ratios. Binary hydrocolloid gels were prepared using three ingredients: two hydrocolloids (total hydrocolloid ...
Hong-Ting Victor Lin +3 more
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Numerical Simulation on Rock-Breaking Mechanism of Axe-shaped Cutter
Axe-shaped cutter has good impact resistance and wear resistance,can improve the rock-breaking efficiency of PDC bit,and is widely used in high abrasive and hard formations.In this paper,based on elastic-plastic mechanics and rock mechanics,taking ...
Gong Junyun, Wu Wenxiu, Zhou Zonggan
doaj
Theoretical and numerical studies of rock breaking mechanism by double disc cutters
A plane mechanical model of rock breaking process by double disc cutter at the center of the cutterhead is established based on contact mechanics to analyze the stress evolution in the rock broken by cutters with different spacings.
Yiqiang Kang +6 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source

