Results 51 to 60 of about 918,244 (327)

Microglandular adenosis of the breast: A case report and a highlight on main diagnosis and management aspects

Current Medicine Research and Practice, 2020
Microglandular adenosis (MA) is a basically benign–recently borderline-breast disease which mimics well differentiated breast carcinoma clinically and pathologically. The incidence of carcinoma associated with MA reaches up to 27%. In this manuscript, we
Omar Hamdy, AbdAllah Elzeiny, Gehad A Saleh, Amany Hassan   +3 more
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Diabetes mellitus and necrotizing fasciitis – a deadly combination; case report [PDF]

, 2020
Necrotizing fasciitis is a rapidly destructive affliction of soft tissues, with a mortality rate that may reach 73% of the cases. It is characterized by a progressive inflammation and extended necrosis of the subcutaneous tissue and the fascia ...
Andronache, Liliana Florina, Bica, Cristina, Gherghiceanu, Florentina, Mazilu, Laura, Moroianu, Lavinia Alexandra, Paunica, Ioana, Sandu, Camelia, Suceveanu, Andra Iulia, Toma, Alexandra   +8 more
core   +3 more sources

Potential Usefulness a Coronal View using an Automated Breast Ultrasound System in Detecting Breast Lesions

European Journal of Breast Health
Objective: An automated breast ultrasound system (ABUS) combined with screening mammography has increased cancer detection rates; however, supplemental ABUS use has increased recall rates.
Megumi Suzuki, Ryohei Nakayama, Kiyoshi Namba, Hiroyuki Kawami, Mayumi Nara, Seigo Nakamura   +5 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Ageing And Cancer As Diseases Of Epigenesis [PDF]

, 2009
Cancer and ageing are often said to be diseases of development. During the past fifty years, the genetic components of cancer and ageing have been intensely investigated since development, itself, was seen to be an epiphenomenon of the genome.
Gilbert, Scott F.
core   +2 more sources

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source

Paget′s disease of the breast

Journal of Carcinogenesis, 2011
Paget's disease of the breast is a rare type of cancer of the nipple-areola complex and that is often associated with an underlying in situ or invasive carcinoma. This article provides an overview and we review the main clinicopathological and therapeutic features of mammary Paget's disease.
openaire   +3 more sources

Comparison of robotic, conventional, and endoscopic nipple-sparing mastectomy with immediate prosthetic breast reconstruction for breast cancer: A systematic review and meta-analysis

Biomolecules & Biomedicine
In this network meta-analysis, we aimed to evaluate the relative efficacy of robotic nipple-sparing mastectomy (RNSM), conventional nipple-sparing mastectomy (CNSM), and endoscope-assisted nipple-sparing mastectomy (ENSM), each combined with immediate ...
Na An, Wenjuan Wang, Dandan Dai, Fei Yuan, Yufeng Zhang   +4 more
doaj   +1 more source