Results 11 to 20 of about 393,599 (169)

Activation of TMEM16A Ca2+-activated Cl− channels by ROCK1/moesin promotes breast cancer metastasis

open access: yesJournal of Advanced Research, 2021
Introduction: Transmembrane protein 16A (TMEM16A) is a Ca2+-activated chloride channel that plays a role in cancer cell proliferation, migration, invasion, and metastasis.
Shuya Luo   +13 more
doaj   +1 more source

NKX2-8/PTHrP Axis-Mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer

open access: yesFrontiers in Oncology, 2022
Bone metastasis is one of the most common distant metastasis of breast cancer, which could cause serious skeletal disease and increased cancer-related death.
Ainiwaerjiang Abudourousuli   +15 more
doaj   +1 more source

Aerosol delivery of small hairpin osteopontin blocks pulmonary metastasis of breast cancer in mice. [PDF]

open access: yesPLoS ONE, 2010
Metastasis to the lung may be the final step in the breast cancer-related morbidity. Conventional therapies such as chemotherapy and surgery are somewhat successful, however, metastasis-related breast cancer morbidity remains high. Thus, a novel approach
Kyeong-Nam Yu   +17 more
doaj   +1 more source

Gingival metastasis of a breast carcinoma [PDF]

open access: yesClinical Case Reports, 2020
AbstractWe report a case of metastasis to the gingiva of breast carcinoma. The breast tumor was treated with neoadjuvant chemotherapy followed by a radical mastectomy associated with axillary dissection. The gingival lesion occurred 7 months after surgery; the metastasis was confirmed by a biopsy.
Moustapha Ndiaye   +13 more
openaire   +3 more sources

Intrameningioma Metastasis of Breast Carcinoma

open access: yesRare Tumors, 2014
Tumor-to-tumor metastasis of breast carcinoma to meningioma is a rare phenomenon. It is likely underdiagnosed given the relatively high prevalence and comorbidity of these two primary tumor types, the lack of standardized methodologies for its diagnosis, and the tendency to obfuscate this lesion with simple meningioma or cerebral metastasis of breast ...
Cha, Soonmee   +7 more
openaire   +4 more sources

Neoadjuvant neratinib promotes ferroptosis and inhibits brain metastasis in a novel syngeneic model of spontaneous HER2+ve breast cancer metastasis

open access: yesBreast Cancer Research, 2019
Background Human epidermal growth factor receptor-2 (HER2)-targeted therapies prolong survival in HER2-positive breast cancer patients. Benefit stems primarily from improved control of systemic disease, but up to 50% of patients progress to incurable ...
Aadya Nagpal   +14 more
doaj   +1 more source

Clinicomics-guided distant metastasis prediction in breast cancer via artificial intelligence

open access: yesBMC Cancer, 2023
Background Breast cancer has become the most common malignant tumour worldwide. Distant metastasis is one of the leading causes of breast cancer-related death.
Chao Zhang   +12 more
doaj   +1 more source

Mechanisms of breast cancer metastasis [PDF]

open access: yesClinical & Experimental Metastasis, 2021
AbstractInvasive breast cancer tends to metastasize to lymph nodes and systemic sites. The management of metastasis has evolved by focusing on controlling the growth of the disease in the breast/chest wall, and at metastatic sites, initially by surgery alone, then by a combination of surgery with radiation, and later by adding systemic treatments in ...
S. David Nathanson   +8 more
openaire   +3 more sources

Integrated Analysis of ceRNA Network Reveals Prognostic and Metastasis Associated Biomarkers in Breast Cancer

open access: yesFrontiers in Oncology, 2021
BackgroundBreast cancer is a malignancy and lethal tumor in women. Metastasis of breast cancer is one of the causes of poor prognosis. Increasing evidences have suggested that the competing endogenous RNAs (ceRNAs) were associated with the metastasis of ...
Da Qian   +9 more
doaj   +1 more source

Loss of sphingosine kinase 1 increases lung metastases in the MMTV-PyMT mouse model of breast cancer.

open access: yesPLoS ONE, 2021
Breast cancer is a very heterogeneous disease, and ~30% of breast cancer patients succumb to metastasis, highlighting the need to understand the mechanisms of breast cancer progression in order to identify new molecular targets for treatment. Sphingosine
Fabiola N Velazquez   +6 more
doaj   +1 more source

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