Results 21 to 30 of about 381,472 (246)

Neoadjuvant neratinib promotes ferroptosis and inhibits brain metastasis in a novel syngeneic model of spontaneous HER2+ve breast cancer metastasis

open access: yesBreast Cancer Research, 2019
Background Human epidermal growth factor receptor-2 (HER2)-targeted therapies prolong survival in HER2-positive breast cancer patients. Benefit stems primarily from improved control of systemic disease, but up to 50% of patients progress to incurable ...
Aadya Nagpal   +14 more
doaj   +1 more source

Integrated Analysis of ceRNA Network Reveals Prognostic and Metastasis Associated Biomarkers in Breast Cancer

open access: yesFrontiers in Oncology, 2021
BackgroundBreast cancer is a malignancy and lethal tumor in women. Metastasis of breast cancer is one of the causes of poor prognosis. Increasing evidences have suggested that the competing endogenous RNAs (ceRNAs) were associated with the metastasis of ...
Da Qian   +9 more
doaj   +1 more source

Clinicomics-guided distant metastasis prediction in breast cancer via artificial intelligence

open access: yesBMC Cancer, 2023
Background Breast cancer has become the most common malignant tumour worldwide. Distant metastasis is one of the leading causes of breast cancer-related death.
Chao Zhang   +12 more
doaj   +1 more source

The relationship between the Hippo signaling pathway and bone metastasis of breast cancer

open access: yesFrontiers in Oncology, 2023
Bone is the most common site of metastasis from breast cancer, which is the most prevalent cancer affecting women globally. Bone metastasis from breast cancer severely affects the quality of life of patients and increases mortality.
Qinyu Han   +5 more
doaj   +1 more source

Loss of sphingosine kinase 1 increases lung metastases in the MMTV-PyMT mouse model of breast cancer.

open access: yesPLoS ONE, 2021
Breast cancer is a very heterogeneous disease, and ~30% of breast cancer patients succumb to metastasis, highlighting the need to understand the mechanisms of breast cancer progression in order to identify new molecular targets for treatment. Sphingosine
Fabiola N Velazquez   +6 more
doaj   +1 more source

Molecular mediators of breast cancer metastasis

open access: yesHematology/Oncology and Stem Cell Therapy, 2021
Breast cancer has the highest incidence rate of malignancy in women worldwide. A major clinical challenge faced by patients with breast cancer treated by conventional therapies is frequent relapse. This relapse has been attributed to the cancer stem cell
Ragini Yeeravalli, Amitava Das
doaj   +1 more source

A novel long non-coding RNA AC073352.1 promotes metastasis and angiogenesis via interacting with YBX1 in breast cancer

open access: yesCell Death and Disease, 2021
Breast cancer is the major cause of cancer death worldwide in women. Patients with metastasis have poor prognosis and the mechanisms of breast cancer metastasis are not completely understood. Long non-coding RNAs (lncRNAs) have been shown to have crucial
Xue Kong   +9 more
doaj   +1 more source

Massive metastasis of breast cancer to female genital organs

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2021
Objective: Breast cancer metastasis to the female genital tract is rare, and the ovaries are the most frequent site of extragenital cancer metastasis. The uterus and cervix have been rarely reported as the site of metastasis.
Ling Lim   +3 more
doaj   +1 more source

Facile construction of gold- and BODIPY-coordinated liposomal nanocomplexes for enhanced photothermal therapy of cancer

open access: yesMaterials & Design
Photothermal therapy (PTT) has attracted extensive attention in cancer treatment because of its advantages of non-invasive and few side effects. Gold nanoparticles and boron-fluorine-dipyrrole (BODIPY) dye have been used as photothermal agents (PTAs ...
Yuran Wang   +5 more
doaj   +1 more source

EGFR-Mutated Breast Metastasis of Lung Adenocarcinoma: A Case Report

open access: yesCase Reports in Oncology, 2015
Breast metastasis from other primary carcinoma is very rare and could be difficult to identify despite immunohistochemistry analysis. Breast metastasis from lung adenocarcinoma can mimic triple-negative breast cancer.
Eric Dansin   +9 more
doaj   +1 more source

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