Results 81 to 90 of about 858,528 (292)

A novel hollow iron nanoparticle system loading PEG-Fe3O4 with C5a receptor antagonist for breast cancer treatment

Frontiers in Immunology
Breast cancer is the most diagnosed malignancy and major cause of cancer death among women population in the worldwide. Ferroptosis is a recently discovered iron-dependent regulated cell death involved in tumor progression and therapeutic response ...
Hong Yang, Guiqing Li, Ji Zhang, Jing Zhao, Yunpei Zhao, Yufei Wu, Zihan Sun, Shuangshuang Song, Ying Zou, Zhihao Zou, Xiao Han, Boshao Deng, Lulu Wang, Hang Rao, Guilian Xu, Shufeng Wang, Sheng Guo, Huanyu Ding, Yan Shi, Yuzhang Wu, Jian Chen   +20 more
doaj   +1 more source

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

Advanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen, Zong Chen, Chenzhi Lai, Yingying Yue, Tian He, Hao Gong, Jing Shi, Xiaoshuang Guo, Yu Wang, Guodong Song, Xiaolei Jin   +10 more
wiley   +1 more source

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen, Yangyi Wang, Tingting Li, Changqing Guo, Zhe Xie, Zhixian Zhang, Xinghua Han, Wei Wang, Jian Wang, Xiaopeng Ma, Yuanzeng Min   +10 more
wiley   +1 more source

Aesthetic preferences for male breast: Analysis of 2282 surveys on the Chinese population

JPRAS Open
Background: As the prevalence of male breast surgery rises in China, there is a growing need to further investigate the aesthetic standards associated with male breasts among Chinese population. Method: An interactive online survey featuring computerized
Saisai Cao, Boyang Wang, Xiangyu Liu
doaj   +1 more source

Visit to Breast test Wales, Cardiff

, 1997
Description of a visit to Visit to Breast test Wales, Cardiff by the National Breast Screening ...
National Breast Screening Programme
core  

Zonal difference and prognostic significance of Foxp3 regulatory T cell infiltration in breast cancer

, 2021
Breast neoplasms; Foxp3 protein; Humans; Regulatory; T ...
임우성, 조민선, 문병인, 박상희, 성순희, 구혜수   +5 more
core   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

“Going Flat”: Aesthetic Flat Closure as a Breast Reconstruction Option in Gender-nonconforming Patients

Plastic and Reconstructive Surgery, Global Open
Summary:. Patients who desire a flatter chest contour after mastectomy can opt for aesthetic flat closure (AFC) instead of traditional autologous and breast implant options that recreate the breast mound. AFC is an evolving area of reconstructive surgery
Karen Li, MD, Rachel N. Rohrich, BS, Christian X. Lava, BS, MS, Sara Marshall, BA, Wynne Zheng, BA, MA, Rebecca Falconer, BS, Kelly Kapp, MD, Lucy De La Cruz, MD, Ian Greenwalt, MD, Kenneth L. Fan, MD   +9 more
doaj   +1 more source

Tumour suppressor EP300, a modulator of paclitaxel resistance and stemness, is down-regulated in metaplastic breast cancer [PDF]

, 2017
Purpose We have previously described a novel pathway controlling drug resistance, epithelial-to-mesenchymal transition (EMT) and stemness in breast cancer cells.
Singh, P, Yague, E, Raguz, S, Ali, S, Lin, ML, Coombes, RC, Asaduzzaman, M, Hu, Y, Gallon, J, Shousha, S, Haoxiang, M, Lam, EWF, Constantinou, S   +12 more
core   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source