Results 101 to 110 of about 858,528 (292)

Data managers : a survey of the European Society of Breast Cancer Specialists (EUSOMA) in certified multidisciplinary breast Centres

open access: yes, 2016
According to an European Parliament deliberation, multidisciplinary breast Centres should be established throughout Europe by 2016. The EUSOMA document “The requirements of a specialist breast centre” defines data managers (DM) as “trained and dedicated
Ponti A.   +8 more
core  

Cancer‐Associated Fibroblasts Promote Glucose Metabolic Reprogramming and Progression of Triple‐Negative Breast Cancer via Exosomal circFAD104‐Mediated Intercellular Communication

open access: yesAdvanced Science, EarlyView.
CAF‐derived exosomes deliver circFAD104 into TNBC cells, where it acts as a molecular scaffold that bridges the E3 ligase MARCHF8 and PGM1, promoting MARCHF8‐mediated K48‐linked ubiquitination and proteasomal degradation of PGM1. Loss of PGM1 redirects glucose‐phosphate flux from glycogen synthesis toward glycolysis, thereby driving stemness, EMT, and ...
Lei Wang   +16 more
wiley   +1 more source

AI‐Powered, Temperature‐Resolved Centrifugal Microfluidics for Rapid 3D Phase‐Diagram Generation of Biomolecular Condensates

open access: yesAdvanced Science, EarlyView.
By merging centrifugal microfluidics, precise temperature control, and AI image recognition, T‐PhaseMap transforms biomolecular condensate phase mapping into a rapid, temperature‐resolved workflow. It generates 3D composition–temperature phase diagrams within 30 min, resolves four phase states, and uncovers temperature‐dependent heparin sodium ...
Jiashuo Li   +6 more
wiley   +1 more source

Oncoplastic Surgery Versus Lumpectomy: Analysis of Oncological Outcomes and Surgical Complications in 1290 Breast Cancer Patients

open access: yesCurrent Oncology
This 12-year retrospective study compared oncoplastic breast-conserving surgery (OBCS) with lumpectomy without reconstruction (LNR) to evaluate surgical and oncological outcomes.
Adolfo Alejandro Lopez Rios   +3 more
doaj   +1 more source

Minutes of the Meeting of the Steering Group for National Breast Screening Programme

open access: yes, 1997
Minutes of a meeting of the Steering Group for National Breast Screening Programme ...
National Breast Screening Group
core  

Hierarchical Flux‐Protection Engineering Stabilizes Oxidation‐Prone Metabolic Nodes for High‐Level Curcumin Biosynthesis

open access: yesAdvanced Science, EarlyView.
Flux‐protection engineering stabilizes an oxidation‐prone L‐DOPA node in engineered E. coli by combining acid‐adapted chassis evolution, respiratory‐chain modulation, enzyme‐level flux matching, and pH–DO control. Carbon is redirected from oxidative browning to productive biosynthesis, enabling 1075.2 mg/L curcumin and demonstrating transferability to ...
Jianbin Chen   +10 more
wiley   +1 more source

Emerging clinical applications of exosomes in breast cancer management from biomarkers to therapeutics

open access: yesDiscover Oncology
Exosomes, nano-sized extracellular vesicles carrying distinct molecular cargoes inherited from their parent cells, have emerged as critical mediators of intercellular communication in cancer. In breast cancer, tumor-derived exosomes (TDEs) possess unique
Xiangmei Wu, Wenjing Wang
doaj   +1 more source

Application of Artificial Intelligence in Breast Ultrasound Diagnosis

open access: yesDiagnostics
Artificial intelligence (AI) is reshaping ultrasound diagnosis by converting operator-dependent grayscale, Doppler, elastography, contrast-enhanced, automated-volume, and video data into reproducible decision support.
Jian Zhang   +3 more
doaj   +1 more source

Ultrasound‐Activated Nanoinhibitors Blocking the Chemo‐Immune Checkpoint to Overcome Chemotherapy‐Induced Immune Resistance

open access: yesAdvanced Science, EarlyView.
A sono‐responsive chemo‐immune checkpoint nanoinhibitor (Sono‐TT8) co‐delivering TPZ chemotherapy and siXkr8 simultaneously kills tumor cells and blocks PS externalization, reversing chemotherapy‐induced immunosuppression and enhancing antitumor immunity. ABSTRACT Breast cancer features an immunosuppressive tumor microenvironment following chemotherapy
Yunfan Liu   +13 more
wiley   +1 more source

Introducing a Novel Anatomic Resuturing Technique: A Comparative Analysis with Dermal Flap Suspension for the Prevention of Postoperative Pseudoptosis in Reduction Mammaplasty

open access: yesTurkish Journal of Plastic Surgery
Introduction: Postoperative pseudoptosis (“bottoming-out”) and upward nipple–areola complex rotation remain important late esthetic problems after reduction mammaplasty. Dermal flap suspension to the pectoralis major fascia provides internal support, but
Şeyda Güray, Cihan Gençtürk
doaj   +1 more source

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