Results 121 to 130 of about 858,528 (292)

Reshaping Breast Cancer Survivorship Through Expanding the Indications for the Omission of Radiation

Current Breast Cancer Reports
Abstract Purpose of Review As greater emphasis is placed on survivorship and long-term morbidity, more attention is being paid to de-escalation. This review examines areas where radiation may be safely omitted without compromising outcomes, thereby improving quality of life for breast cancer ...
Michael S. Sabel, Elizabeth M. Jaworski
openaire   +1 more source

Breast Cancer Tissue Bank Search Tool

The Research Query page is a component of the Breast Cancer Tissue Bank website. It shows the numbers of consented patients, and the numbers of available samples.

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Dual‐Targeted Biomimetic MoSe2 Nanozymes for Enhancing Peri‐Implant Soft Tissue Integration

Advanced Science, EarlyView.
A dual‐targeting biomimetic nanozyme, MoSe2@SPMM, selectively targets Staphylococcus aureus and oxidatively stressed macrophages. Near‐infrared activation couples contact‐enhanced photothermal bacterial eradication with reactive oxygen species scavenging to disrupt the pathogenic–immunological amplification loop.
Minghao Zhou, Miaomiao Tian, Jingwei Yu, Jiaxin Kang, Miaomiao Chen, Yue Yuan, Lizhi Liu, Hongbo Wei   +7 more
wiley   +1 more source

Adaptive Network Stabilization Despite Profound Structural Reorganization in Human Organotypic Cultures

Advanced Science, EarlyView.
Adult human organotypic cortical slices undergo marked neuronal loss, laminar disruption, and glial activation, yet their network activity progressively stabilizes after a variable period. Electrophysiology, longitudinal calcium imaging, and quantitative histology show that structurally remodeled human circuits show adaptive capacity resulting in ...
Estilla Zsófia Tóth, Rebeka Stelcz, Réka Bod, Ábel Petik, Eszter Juhász, Kinga Tóth, Liza Szalai, Nour Essam, Fanni Somogyi, Beatrix Kovács, Amirmahdi Mojtahedzadeh, Attila György Bagó, Loránd Erőss, Péter Orbay, Johanna Petra Szabó, Dániel Fabó, Boglárka Hajnal, Bence Rácz, Daniel Hillier, István Ulbert, Lucia Wittner   +20 more
wiley   +1 more source

BRCA1/2 variant landscape and clinical correlates in high-risk breast cancer patients from Eastern China

Frontiers in Oncology
IntroductionGlobal advances in genetic testing are reshaping breast cancer management. Although large unselected Chinese cohorts have been reported, the BRCA1 and BRCA2 (BRCA1/2) variant landscape specifically in high-risk, clinically referred ...
Wei Gu, Wei Gu, Wei Gu, Najeeb Ullah Khan, Huijun Lei, Huijun Lei, Jinzhen Fu, Jinzhen Fu, Jinzhen Fu, Chengyin Xu, Chengyin Xu, Xukai Chen, Xukai Chen, Xiao-jia Wang, Xiao-jia Wang, Tianhui Chen, Tianhui Chen, Tianhui Chen   +17 more
doaj   +1 more source

BCTB Invasive Breast Cancer Samples and Images

This BCTB subcollection contains breast tissue and blood samples, and associated images, where a diagnosis of invasive cancer has been determined by a ...

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Isocyanate‐Modified Melatplatin(IV) Enhances Antitumor Efficacy via TCF4/COL6A3‐Mediated Extracellular Matrix Remodeling and cGAS‐STING Pathway Activation in Bladder Cancer

Advanced Science, EarlyView.
A series of melatonin‐conjugated platinum(IV) prodrugs was functionalized with isocyanate chains (compounds 5‒12). MP‐12C (compound 11) was identified as the lead candidate, with optimal potency and safety. MP‐12C exhibited greater efficacy than cisplatin by increasing intracellular uptake, reshaping the extracellular matrix, activating the cGAS‐STING ...
Linhui Wang, Xiaomeng Liu, Tao Zhu, Zirun Su, Ruiping Liu, Zhe Li, Kaixuan Du, Kaipeng Jia, Chong Fu, Yuda Lin, Zihan Xue, Zhe Zhang, Chong Shen, Yunkai Qie, Zhouliang Wu, Zhiheng Liu, Kangkang Liu, Jingyuan Xu, Hailong Hu   +18 more
wiley   +1 more source

SPOCK1 promotes the progression of breast cancer by modulating cancer-associated fibroblasts and exerts a synergistic effect with ANXA2

Frontiers in Oncology
BackgroundSPOCK1, a matricellular glycoprotein, has been implicated in tumor progression, metastasis, and the tumor immune microenvironment, yet its specific roles in breast cancer (BRCA) remain unclear.
Yuan Jie, Xin Fei, Meng Fan
doaj   +1 more source

The human microbiome reshapes the breast cancer immune-metabolic-hormonal microenvironment

Frontiers in Immunology
Beyond established risk factors such as genetics and hormones, the human microbiome has emerged as a pivotal player in breast cancer pathogenesis. This review delineates the technological evolution in breast microbiome research, spanning traditional culture methods to high-throughput sequencing and cutting-edge spatial omics.
Qianheng Wang, Furong Zhang, Yue Xin, Rui Yang, Zimei Tang, Zhenghao Wu, Jie Ming   +6 more
openaire   +1 more source

BCTB Non-Invasive Breast Cancer Samples and Images

This BCTB subcollection contains breast tissue and blood samples, and associated images, where a diagnosis of non-invasive cancer has been determined by a ...

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