Results 81 to 90 of about 9,751 (308)

Dual‐Functional Ingestible Passive Capsules for High‐Throughput Intestinal Sampling with Sealed Containment and Targeted Drug Delivery

open access: yesAdvanced Robotics Research, EarlyView.
To address challenges in high‐throughput intestinal sampling with sealed containment and target drug delivery, we developed a dual‐functional ingestible passive capsule with a dual‐triggered control system based on pH‐response and mechanical actuation.
Libing Huang   +9 more
wiley   +1 more source

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

open access: yesAdvanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang   +10 more
wiley   +1 more source

MHD mixed convection flow in the WCLL: heat transfer analysis and cooling system [PDF]

open access: yes, 2019
In the Water-Cooled Lithium Lead (WCLL) blanket, a critical problem faced by the design is to ensure that the breeding zone (BZ) is properly cooled by the refrigeration system to keep the structural materials under the maximum allowed temperature by the ...
Caruso, Gianfranco   +3 more
core   +1 more source

FUSED SALTS AS THERMONUCLEAR REACTOR BREEDER BLANKETS

open access: yes, 1958
The use of fused lithium nitrate as a breeding material for thermonuclear reactors is proposed. Some of the properties of LiNO/sub 3/ such as thermal stability, radiation stability, neutron reaction products, and corrosive effects are briefly considered. Further studies are suggested. (D.E.B.)
openaire   +3 more sources

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

open access: yesAdvanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen   +4 more
wiley   +1 more source

Water-cooled lead and ceramic breeder (WLCB) breeding blanket (BB) for the EU DEMO: Neutronic campaigns for T breeding optimization

open access: yesNuclear Materials and Energy
A novel Breeding Blanket (BB) concept, the Water-cooled Lead and Ceramic Breeder (WLCB) BB, has been developed under the EUROfusion Programme to address key challenges identified during the Pre-Conceptwual Design (PCD) phase for the driver BB concepts ...
Iole Palermo   +6 more
doaj   +1 more source

Optimization of Electron Beam Welding Joint of Water-Cooled Ceramic Breeder Blanket. [PDF]

open access: yesMaterials (Basel), 2021
Zhang Y   +8 more
europepmc   +1 more source

IL‐3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
IL‐3 recruits PRDX1 through IL‐3R to modulate the inflammatory response of microglia via the KEAP1‐NRF2‐HO‐1/NF‐κB pathway to attenuate neuroinflammation in traumatic brain injury. ABSTRACT Microglia play a crucial role in the progression of neuroinflammation following traumatic brain injury (TBI). Interleukin‐3 (IL‐3), a significant regulatory factor,
Nana Huang   +18 more
wiley   +1 more source

Analysis of a segmentation approach to breeder blanket design and the utilisation of FLiBe as a novel neutron reflector

open access: yesNuclear Fusion
Tritium production in a fusion reactor is essential for a deuterium-tritium burning plasma source, and designing a lithium-containing breeder blanket is crucial for a closed fuel cycle in an electricity-to-grid power plant.
Adam J. Barker   +2 more
doaj   +1 more source

A Solid breeder tokamak blanket designed for failure mode operation [PDF]

open access: yes, 1977
Statement of responsibility on title-page reads: Franklin Chen, Peter Griffith, Thomas McManamy, and Gary Was"May 1977.""This study is basically an integration and extension of a doctor's thesis by Franklin Chen and a master's thesis by Gary Was ...
Chen, Franklin Fun Kun   +3 more
core  

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