Results 111 to 120 of about 1,131,323 (347)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

THE RESPONSE OF SEVERAL TOMATO CULTIVARS FOR PROCESSING IN CENTRAL TRANSYLVANIA CONDITIONS. I. YIELD CAPACITY

open access: yesNotulae Botanicae Horti Agrobotanici Cluj-Napoca, 2006
Nine tomato varieties, hybrids F1 and selection (Perla Clujului, Natalia, Chico Grande, Indiana, Red River, Event, Jet, Montego, Cluj 8-2002) have been tested for their yield characteristics and compared in order to experiment and control, at Fruit ...
Mihai JIDAVU   +6 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Software Selegen-REML/BLUP: a useful tool for plant breeding

open access: yes, 2016
The software Selegen-REML/BLUP uses mixed models, and was developed to optimize the routine of plant breeding programs. It addresses the following plants categories: allogamous, automagous, of mixed mating system, and of clonal propagation.
M. Resende
semanticscholar   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Genetic relationships of some local and introduced grapes (Vitis vinifera L.) by microsatellite markers

open access: yesBiotechnology & Biotechnological Equipment, 2019
In this study, the genetic relationships of 29 grape genotypes were defined with six SSR (simple sequence repeat) markers, and 65 polymorphic bands were identified, with matrix correlation (r) of 0.79.
Burçak Işçi
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

DNA fingerprints applied to gene introgression in breeding programs. [PDF]

open access: bronze, 1990
J. Hillel   +6 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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