Results 121 to 130 of about 1,131,323 (347)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

EVALUATION OF HYBRIDS FROM SIMPLE CROSSES USING MAIZE ELITE LANDRACES WITH FORAGE OUTSTANDING CHARACTERISTICS FOR A MEXICAN ARID LAND

open access: yesTropical and Subtropical Agroecosystems, 2013
The Comarca Lagunera region is the most important area of maize forage in México. In this region; which is shared by the Mexican States of Coahuila and Durango, are used a great amount of hybrids and varieties of maize imported from other countries ...
José L. García Hernández   +6 more
doaj  

Shifting the limits in wheat research and breeding using a fully annotated reference genome

open access: yesScience, 2018
R. Appels   +200 more
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Biometrical analysis and selection of tetraploid progenies of Panicum maximum using mixed model methods

open access: yesPesquisa Agropecuária Brasileira, 2004
The objectives of this work were to estimate the genetic and phenotypic parameters and to predict the genetic and genotypic values of the selection candidates obtained from intraspecific crosses in Panicum maximum as well as the performance of the hybrid
Resende Rosangela Maria Simeão   +3 more
doaj  

Agriculture modifies the seasonal decline of breeding success in a tropical wild bird population [PDF]

open access: hybrid, 2014
Samantha J. Cartwright   +4 more
openalex   +1 more source

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