Results 101 to 110 of about 206,879 (306)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Bitter gourd, Momordica charantia L., breeding lines differ in secondary metabolite content according to market type

open access: yesJournal of Applied Botany and Food Quality, 2019
Bitter gourd, Momordica charantia L., is an important commercial cucurbitaceous vegetable of enormous medicinal value in Asia because of its secondary metabolite content.
Bernhard Trierweiler   +8 more
doaj   +1 more source

Expression of Fusarium wilt resistant gene, FocBo1, in association with disease resistant phenotypes of cabbage breeding lines

open access: yes, 2015
Fusarium wilt, caused by a fungal pathogen Fusarium oxysporum f. sp. conglutinans (Foc), is a destructive disease of Brassica oleracea var. capitata. Currently, there are reports concerning molecular markers linked to Fusarium wilt disease resistance ...
M R Kim   +3 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

BREEDING FORAGE-GRAIN CULTURES IN THE VOLGA REGION

open access: yesВ мире научных открытий, 2016
With the aim of creating varieties forage-grain directions for a ten years, conducted a comprehensive assessment of 80 lines of grain sorghum, 55 lines of sweet sorghum, 70 lines of Sudan grass and 15 varieties and lines of foxtail millet.
Elena Aleksandrovna Vertikova
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

ЕФЕКТ НА РАЗЛИЧНИ ИЗТОЧНИЦИ НА СПЕЦИФИЧЕН ВАРИАНС ВЪРХУ НЯКОИ ПРОДУКТИВНИ ПРИЗНАЦИ НА ОВЦЕ ОТ МЕДНОЧЕРВЕНАТА ШУМЕНСКА ПОРОДА

open access: yesЖивотновъдни науки, 2014
An investigation with 318 sheep from the Copper-Red Shumen breed during the period 2003-2010, originated from Kabiuk herd, Shumen was carried out. Parameters live weight at weaning, 9 months, 1.5 years and 2.5 years of age, wool productivity traits ...
ГЕНОВЕВА СТАЙКОВА
doaj  

The efficiency of selection in the early generations of a potato breeding programme

open access: yes, 2015
The efficiency of selection in the early generations of a potato breeding programme is examined. A number of unselected potato (Solanum tuberosum L) clones were grown in a glasshouse, from true botanical seed, and thereafter in the field at two ...
Brown, Jack
core  

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