Results 101 to 110 of about 207,701 (306)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Reproductive challenges in abalone breeding [PDF]
, 2021 Abalone aquaculture in many countries has only recently closed the on-farm life cycle (managing all stages from production to reproduction) due to pressure on wild stocks and a move towards selective breeding for genetic improvement.
Mendoza-Porras, Omar +4 more
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Seedling Resistance to Stagonospora nodorum Blotch in Wheat Genotypes [PDF]
, 2013 In two independent experiments set up in the greenhouse the seedling resistance to Stagonospora nodorum blotch was investigated in 92 varieties, breeding lines and genotypes with a known genetic background.
Csősz, Lászlóné +4 more
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Molecular Genetics, Genomics, and Biotechnology in Crop Plant Breeding [PDF]
, 2020 A diverse set of molecular markers techniques have been developed over the last almost 40 years and used with success for breeding a number of major crops.
Søren K. Rasmussen +1 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Животновъдни науки, 2014 An investigation with 314 sheep from the Karakachan breed during the period 2003-2010, originated from Kabiuk herd, Shumen was carried out. Parameters live weight at weaning, 9 months, 1.5 years and 2.5 years of age, wool productivity traits - quantity ...
ГЕНОВЕВА СТАЙКОВА +1 more
doaj
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
The impact of longline fishing on the seabirds breeding on Marion Island [PDF]
, 2002 Includes bibliographical references.This study describes the impact of longline fishing on the seabirds breeding on the sub-Antarctic Prince Edward Islands.
Nel, Deon Charl
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Resistance To Powdery Mildew In Selected Czech Winter Barley Breeding Lines
Czech Journal of Genetics and Plant Breeding, 2005 Powdery mildew resistances in Czech winter barley breeding lines were postulated on the basis of their reaction types to 32 pathotypes of the pathogen with different combinations of virulence genes.
A Dreiseitl
doaj +1 more source