Results 61 to 70 of about 2,145,263 (295)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Line breeding of sheep when creating a new type of Transbaikal breed

Siberian Herald of Agricultural Science, 2020
The role of line breeding in fine-wool sheep husbandry is shown. Productivity indicators of fine-wool sheep of Transbaikal breed of Khangil type, in the conditions of Trans-Baikal Territory are presented. Four inbred lines were created in the Khangil type of Transbaikal breed, which are distinguished by increased indicators of wool and meat ...
T. N. Khamiruev, I. V. Volkov, B. Z. Bazaron   +2 more
openaire   +1 more source

Study of some resistance mechanisms to Orobanche spp. infestation in faba bean (Vicia faba L.) breeding lines in Tunisia

Plant Production Science, 2016
The behavior of seven faba bean breeding lines toward Orobanche foetida and Orobanche crenata infestation was examined under field, pots, and in vitro conditions and compared to reference cultivars.
Imen Trabelsi, Zouhaier Abbes, Moez Amri, Mohamed Kharrat   +3 more
doaj   +1 more source

Statistical and graphical (GGE biplot) evaluation of the adaptive ability and stability of winter barley breeding lines

Вавиловский журнал генетики и селекции, 2019
Due to current global climate changes, the issue of improving adaptive capacity of crops is of high importance. It is important to create winter crop varieties with both ecological adaptability and yield stability in years with different hydrothermal ...
V. N. Gudzenko
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Common bean breeding to improve red grain lines [PDF]

, 2011
The purpose of this study was to evaluate the performance potential of red bean lines, derived from populations of the first cycle of recurrent selection in the common bean breeding program of the Federal University of Viçosa, Minas Gerais.
Menezes Júnior, José Ângelo Nogueira de, Carneiro, José Eustáquio de Souza, Silva, Vanessa Maria Pereira e, Silva, Lêlisângela Carvalho da, Peternelli, Luiz Alexandre, Carneiro, Pedro Crescêncio Souza   +5 more
core  

Seedling Resistance to Stagonospora nodorum Blotch in Wheat Genotypes [PDF]

, 2013
In two independent experiments set up in the greenhouse the seedling resistance to Stagonospora nodorum blotch was investigated in 92 varieties, breeding lines and genotypes with a known genetic background.
Csősz, Lászlóné, Gál, Mariann, Veisz, Ottó Bálint, Károlyiné Cséplő, Mónika, Vida, Gyula   +4 more
core   +2 more sources

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Development of thermo-photo sensitive genic male sterile lines in wheat using doubled haploid breeding

BMC Plant Biology, 2020
Background Two-line hybrid wheat system using thermo-photo sensitive genic male sterility (TPSGMS) is currently the most promising approach for wheat heterosis utilization in China.
Hongsheng Li, Shaoxiang Li, Sedhom Abdelkhalik, Armaghan Shahzad, Jian Gu, Zhonghui Yang, Mingliang Ding, Kun Liu, Hong Zhao, Mujun Yang   +9 more
doaj   +1 more source