Results 71 to 80 of about 2,145,263 (295)

Genetic structure analysis and identifying key founder inbred lines in diverse elite sub-tropical maize inbred lines

open access: yesScientific Reports, 2023
Understanding the genetic relationships between the key founder inbred lines and derived inbred lines could provide insight into the breeding history and the structure of genetic diversity of the available elite inbred lines with desirable target traits.
Melaku Gedil   +9 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Diallel mixed-model analyses to select superior maize parental lines for Azospirillum brasilense and nitrogen-use efficiency

open access: yes, 2018
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Breeding new maize varieties that take up more N from the soil and increase N fixation is a crucial source of combined nitrogen in agricultural systems.
Amaral, Camila Baptista do [UNESP]   +7 more
core   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

An Analysis of the Genetic Diversity of Bread Wheat x Spelt Breeding Lines in Terms of Their Resistance to Powdery Mildew and Leaf Rust

open access: yes, 2020
The main aim of this study was to analyze the genetic diversity of breeding lines derived from bread wheat and spelt (bread wheat cvs. Zebra, Torka and Kontesa; spelt breeding lines S10–S14) in terms of their resistance to infections caused by ...
Adrian Duba   +3 more
core   +1 more source

Minnesota 101 Muskmelon Breeding Line

open access: yesHortScience, 1984
Abstract Minnesota 101 is a monoecious, short intemode breeding line of muskmelon, Cucumis melo L. Its primary use is envisaged as that of a breeding line useful as a parent in the production of F 1 hybrid cultivars, and as germplasm ...
D. W. Davis, T. J. Kalb, M. A. Shehata
openaire   +1 more source

Tritordeum as a Habitat for the Development of the Rice Weevil Sitophilus oryzae L.—Analysis of Selected Properties of the Cereal Grains Determining Their Resistance Mechanisms

open access: yesAgriculture
In the face of the global climate and ecological crisis, as well as growing consumer needs and demands, a transformation of the global food production and distribution system is necessary.
Mariusz Nietupski   +4 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

FLBG-1 Pepper Breeding Line

open access: yesHortScience, 1983
Abstract FLBG-1 is a sweet pepper (Capsicum an-nuum L.) breeding line that has been tested to be immune to Florida strains of tobacco etch (TEV) and potato Y (PVY) viruses. It is also tolerant to pepper mottle virus (PeMoV). FLBG-1 could be a useful parent for breeding virus-
R. Subramanya, H. Y. Ozaki, T. A. Zitter
openaire   +1 more source

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