Results 41 to 50 of about 11,811 (216)

MicroRNA-155 expression is independently predictive of outcome in chordoma. [PDF]

open access: yes, 2015
BackgroundChordoma pathogenesis remains poorly understood. In this study, we aimed to evaluate the relationships between microRNA-155 (miR-155) expression and the clinicopathological features of chordoma patients, and to evaluate the functional role of ...
Choy, Edwin   +9 more
core   +3 more sources

A nationwide 12‐month observatory of automated insulin delivery shows improved glucose control, sustained adoption, and reduced acute severe events

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1179-1190, February 2026.
Abstract Aims A nationwide observational study was conducted to assess the 12‐month effectiveness of AID systems in the routine care of people with Type 1 diabetes (PwT1D). Methods All PwT1D, adults, and children, who initiated AID between January 1, 2022, and December 31, 2022, were included across 79 centres.
Jean‐Pierre Riveline   +98 more
wiley   +1 more source

Real Results: Why Strategic Philanthropy is Social Justice Philanthropy [PDF]

open access: yes, 2013
The crises affecting our nation and the world have prompted philanthropists to become more organized, focused and, perhaps above all, "strategic" in their efforts.
Kevin Laskowski, Niki Jagpal
core  

First-line therapy in HER2 positive metastatic breast cancer. Is the mosaic fully completed or are we missing additional pieces? [PDF]

open access: yes, 2016
The discovery of human epidermal growth factor receptor 2 (HER2) and its role in the biology of breast cancer and the subsequent development of HER2-targeted therapies, have dramatically improved clinical outcomes for women with early-stage and advanced ...
Cognetti F.   +3 more
core   +2 more sources

Natural Products Targeting the EGFR/HER2 Axis in Tumorigenesis: Interpretation of Molecular Mechanisms and Recent Insights Into Synergistic Strategies for Cancer Therapy

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
Schematic overview illustrating the anticancer mechanisms of selected natural products (resveratrol, quercetin, berberine) targeting EGFR and HER2 signaling pathways in tumor cells. These compounds inhibit receptor activation and downstream oncogenic cascades, including PI3K/Akt/mTOR, MAPK/ERK, and STAT3 pathways.
Iman Ramli   +8 more
wiley   +1 more source

A Scoping Review of Noncommunicable Disease Programs Evaluation: Bridging Gaps and Improving Frameworks in Primary Healthcare

open access: yesHealth Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Effective evaluation is critical for improving non‐communicable disease (NCD) programs. This scoping review explores evaluation methods at the primary healthcare (PHC) level, examines the evaluation process, maps key dimensions and indicators, and identifies related challenges.
Aboalfazl Marvi   +6 more
wiley   +1 more source

Finite difference time domain simulation of the Earth-ionosphere resonant cavity: Schumann resonances [PDF]

open access: yes, 2005
This paper presents a numerical approach to study the electrical properties of the Earth's atmosphere. The finite-difference time-domain (FDTD) technique is applied to model the Earth's atmosphere in order to determine Schumann resonant frequencies of ...
Craddock, IJ   +5 more
core   +2 more sources

The Prognostic Value of Troponin in Acute Pulmonary Embolism: A Systematic Review and Meta‐Analysis

open access: yesCatheterization and Cardiovascular Interventions, Volume 106, Issue 7, Page 3899-3916, December 1, 2025.
ABSTRACT Acute pulmonary embolism (PE) is a major cause of cardiovascular morbidity and mortality. Troponin elevation is increasingly used for risk stratification, but its prognostic utility remains variably reported across studies. To evaluate the prognostic value of troponin elevation in patients with acute PE, concerning short‐term mortality and ...
Ahmed T. Elmewafy   +4 more
wiley   +1 more source

Method of Dose Delivery in Brachytherapy for Cervical Cancer

open access: yesДоклады Белорусского государственного университета информатики и радиоэлектроники, 2023
A method is proposed for delivering an absorbed dose to a target during brachytherapy for cervical cancer by using a new applicator, which consists of an annular part and two uterine canals.
D. I. Kazlouski   +6 more
doaj   +1 more source

Modulation of Membrane and Reserve Fatty Acids of the Thraustochytrid Aurantiochytrium mangrovei by Light and Temperature Culture Conditions

open access: yesLipids, Volume 60, Issue 6, Page 491-505, November 2025.
ABSTRACT This study aimed to investigate the effects of temperature, illumination, and growth stage on the cell morphology, lipid content, and fatty acid (FA) composition in neutral lipids (NL) and polar lipids (PL) of Aurantiochytrium mangrovei, a thraustochytrid, widely known for its capacity to accumulate docosahexaenoic acid (22:6n‐3, DHA ...
Mariana Ventura   +6 more
wiley   +1 more source

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