Results 31 to 40 of about 2,771 (230)

Comparative analysis of three brevetoxin-associated bottlenose dolphin (Tursiops truncatus) mortality events in the Florida Panhandle region (USA). [PDF]

PLoS ONE, 2012
In the Florida Panhandle region, bottlenose dolphins (Tursiops truncatus) have been highly susceptible to large-scale unusual mortality events (UMEs) that may have been the result of exposure to blooms of the dinoflagellate Karenia brevis and its ...
Michael J Twiner, Leanne J Flewelling, Spencer E Fire, Sabrina R Bowen-Stevens, Joseph K Gaydos, Christine K Johnson, Jan H Landsberg, Tod A Leighfield, Blair Mase-Guthrie, Lori Schwacke, Frances M Van Dolah, Zhihong Wang, Teresa K Rowles   +12 more
doaj   +2 more sources

Epicortical Brevetoxin Treatment Promotes Neural Repair and Functional Recovery after Ischemic Stroke

Marine Drugs, 2020
Emerging literature suggests that after a stroke, the peri-infarct region exhibits dynamic changes in excitability. In rodent stroke models, treatments that enhance excitability in the peri-infarct cerebral cortex promote motor recovery. This increase in
Erica Sequeira, Marsha L. Pierce, Dina Akasheh, Stacey Sellers, William H. Gerwick, Daniel G. Baden, Thomas F. Murray   +6 more
doaj   +2 more sources

Profiling of Brevetoxin Metabolites Produced by Karenia brevis 165 Based on Liquid Chromatography-Mass Spectrometry

Toxins, 2021
In this study, Karenia brevis 165 (K. brevis 165), a Chinese strain, was used to research brevetoxin (BTX) metabolites. The sample pretreatment method for the enrichment of BTX metabolites in an algal culture medium was improved here.
Huihui Shen, Xiuxian Song, Yue Zhang, Peipei Zhang, Jing Li, Weijia Song, Zhiming Yu   +6 more
doaj   +2 more sources

Brevetoxin and Conotoxin Interactions with Single-Domain Voltage-Gated Sodium Channels from a Diatom and Coccolithophore

Marine Drugs, 2021
The recently characterized single-domain voltage-gated ion channels from eukaryotic protists (EukCats) provide an array of novel channel proteins upon which to test the pharmacology of both clinically and environmentally relevant marine toxins.
Ping Yates, Julie A. Koester, Alison R. Taylor   +2 more
doaj   +2 more sources

Determination of brevetoxin in recent marine sediments [PDF]

Chemosphere, 2008
Harmful algal blooms (HAB) of Karenia brevis (K. brevis) produce a suite of lipid soluble polyether brevetoxins, known to cause environmental, health and economic ill effects. There is evidence that K. brevis has increased in abundance over the past 50 years, but the dataset is incomplete.
Wilson G, Mendoza, Ralph N, Mead, Larry E, Brand, Damian, Shea   +3 more
openaire   +3 more sources

Spectroscopic ellipsometry methods for brevetoxin detection

Talanta, 2022
The spectroscopic ellipsometry (SE), and attenuated internal reflection spectroscopic ellipsometry (TIRE) are promising methods in label-free biosensing applications. An ellipsometer running under surface plasmon resonance (SPR) conditions has unique advantages over other SPR-based methods in terms of sensitivity and real-time/label-free measurement ...
Mustafa Oguzhan Caglayan, Zafer Üstündağ, Samet Şahin   +2 more
openaire   +3 more sources

"Algal-dromes": a novel conceptual approach to illness in humans exposed to harmful algal bloom toxins. [PDF]

Front Toxicol
Although adverse health effects from harmful algal bloom (HAB) toxins have been described since antiquity, the true worldwide incidence and disease burden has yet to be defined.
Johnson B, Richlen M, Lai J, Twiner MJ.
europepmc   +2 more sources

Stimulation of Neurite Outgrowth in Cerebrocortical Neurons by Sodium Channel Activator Brevetoxin-2 Requires Both N-Methyl-D-aspartate Receptor 2B (GluN2B) and p21 Protein (Cdc42/Rac)-Activated Kinase 1 (PAK1)

Marine Drugs, 2022
N-methyl-D-aspartate (NMDA) receptors play a critical role in activity-dependent dendritic arborization, spinogenesis, and synapse formation by stimulating calcium-dependent signaling pathways.
Suneet Mehrotra, Marsha L. Pierce, Shashank M. Dravid, Thomas F. Murray   +3 more
doaj   +2 more sources

Effects of Four Marine Toxins on Murine Hepatic Biotransformation Enzymes. [PDF]

Toxins (Basel)
This study assesses the impact of sublethal levels of four marine toxins ciguatoxin (CTX-1), maitotoxin-2 (MTX-2), saxitoxin (STX) and brevetoxin-2 (BTX-2) on murine hepatic detoxification enzymes expressed in mouse liver.
Soto de Jesus J, González-Keelan C, Meléndez PA, Cadilla CL, Contreras J, Jiménez-Vélez BD.   +5 more
europepmc   +2 more sources

Design of a Duplex-to-Complex Structure-Switching Approach for the Homogeneous Determination of Marine Biotoxins in Water. [PDF]

Toxins (Basel)
In this report, we describe a fluorescent assay for the detection of six marine toxins in water. The mechanism of detection is based on a duplex-to-complex structure-switching approach.
Al-Tabban A, Rhouati A, Fataftah A, Cialla-May D, Popp J, Zourob M.   +5 more
europepmc   +2 more sources