Results 41 to 50 of about 1,095 (165)

Comparative analysis of three brevetoxin-associated bottlenose dolphin (Tursiops truncatus) mortality events in the Florida Panhandle region (USA).

PLoS ONE, 2012
In the Florida Panhandle region, bottlenose dolphins (Tursiops truncatus) have been highly susceptible to large-scale unusual mortality events (UMEs) that may have been the result of exposure to blooms of the dinoflagellate Karenia brevis and its ...
Michael J Twiner, Leanne J Flewelling, Spencer E Fire, Sabrina R Bowen-Stevens, Joseph K Gaydos, Christine K Johnson, Jan H Landsberg, Tod A Leighfield, Blair Mase-Guthrie, Lori Schwacke, Frances M Van Dolah, Zhihong Wang, Teresa K Rowles   +12 more
doaj   +1 more source

Molecular Determinants of Brevetoxin Binding to Voltage-Gated Sodium Channels

Toxins, 2019
Brevetoxins are produced by dinoflagellates such as Karenia brevis in warm-water red tides and cause neurotoxic shellfish poisoning. They bind to voltage-gated sodium channels at neurotoxin receptor 5, making the channels more active by shifting the ...
Keiichi Konoki, Daniel G. Baden, Todd Scheuer, William A. Catterall   +3 more
doaj   +1 more source

First Light Demonstration of Red Solar Induced Fluorescence for Harmful Algal Bloom Monitoring

Geophysical Research Letters, Volume 50, Issue 13, 16 July 2023., 2023
Abstract The risks harmful algal blooms (HAB) pose to aquatic ecosystems, public health, and coastal economies necessitate supplementation of current observation strategies. Herein, we explore the use of red solar induced fluorescence (SIF) from the TROPOspheric Monitoring Instrument (TROPOMI), a remote sensing measurement retrievable in variable cloud
Kelly Luis, Philipp Köhler, Christian Frankenberg, Michelle Gierach   +3 more
wiley   +1 more source

Concurrent exposure of bottlenose dolphins (Tursiops truncatus) to multiple algal toxins in Sarasota Bay, Florida, USA.

PLoS ONE, 2011
Sentinel species such as bottlenose dolphins (Tursiops truncatus) can be impacted by large-scale mortality events due to exposure to marine algal toxins.
Michael J Twiner, Spencer Fire, Lori Schwacke, Leigh Davidson, Zhihong Wang, Steve Morton, Stephen Roth, Brian Balmer, Teresa K Rowles, Randall S Wells   +9 more
doaj   +1 more source

Calcium Increase and Substance P Release Induced by the Neurotoxin Brevetoxin-1 in Sensory Neurons: Involvement of PAR2 Activation through Both Cathepsin S and Canonical Signaling

Cells, 2020
Red tides involving Karenia brevis expose humans to brevetoxins (PbTxs). Oral exposition triggers neurotoxic shellfish poisoning, whereas inhalation induces a respiratory syndrome and sensory disturbances.
Ophélie Pierre, Maxime Fouchard, Paul Buscaglia, Nelig Le Goux, Raphaël Leschiera, Olivier Mignen, Joachim W. Fluhr, Laurent Misery, Raphaële Le Garrec   +8 more
doaj   +1 more source

The Effects of the Harmful Algal Bloom Species Karenia brevis on Survival of Red Porgy (Pagrus pagrus) Larvae

Toxins, 2022
The harmful algal bloom species, Karenia brevis, forms annual, often intense blooms in the Gulf of Mexico, particularly along the west Florida shelf. Though the ability of K.
Richard Wayne Litaker, Alex K. Bogdanoff, Donnie Ransom Hardison, William C. Holland, Andrew Ostrowski, James A. Morris   +5 more
doaj   +1 more source

Structure Activity Relationship of Brevenal Hydrazide Derivatives

Marine Drugs, 2014
Brevenal is a ladder frame polyether produced by the dinoflagellate Karenia brevis. This organism is also responsible for the production of the neurotoxic compounds known as brevetoxins. Ingestion or inhalation of the brevetoxins leads to adverse effects
Allan Goodman, Jennifer R. McCall, Henry M. Jacocks, Alysha Thompson, Daniel Baden, William M. Abraham, Andrea Bourdelais   +6 more
doaj   +1 more source

Acute Effects of Brevetoxin-3 Administered via Oral Gavage to Mice

Marine Drugs, 2023
Brevetoxins (BTXs) constitute a family of lipid-soluble toxic cyclic polyethers mainly produced by Karenia brevis, which is the main vector for a foodborne syndrome known as neurotoxic shellfish poisoning (NSP) in humans.
Peggy Barbe, Jordi Molgó, Robert Thai, Apolline Urman, Denis Servent, Nathalie Arnich, Mathilde Keck   +6 more
doaj   +1 more source

Synthesis, Modeling, and Biological Evaluation of Analogues of the Semisynthetic Brevetoxin Antagonist β‐Naphthoyl‐Brevetoxin [PDF]

ChemBioChem, 2007
AbstractBrevetoxins are neurotoxic compounds produced by the dinoflagellate Karenia brevis. Extensive blooms induce neurotoxic shellfish poisoning (NSP) and asthma‐like symptoms in humans. β‐naphthoyl‐brevetoxin, the first semisynthetic brevetoxin antagonist, has been defined as the lead compound in the investigation of the mechanisms of ...
Sophie, Michelliza, William M, Abraham, Henry M, Jacocks, Thomas, Schuster, Daniel G, Baden   +4 more
openaire   +2 more sources

Brevenal inhibits pacific ciguatoxin-1B-induced neurosecretion from bovine chromaffin cells.

PLoS ONE, 2008
Ciguatoxins and brevetoxins are neurotoxic cyclic polyether compounds produced by dinoflagellates, which are responsible for ciguatera and neurotoxic shellfish poisoning (NSP) respectively. Recently, brevenal, a natural compound was found to specifically
César Mattei, Peter J Wen, Truong D Nguyen-Huu, Martha Alvarez, Evelyne Benoit, Andrea J Bourdelais, Richard J Lewis, Daniel G Baden, Jordi Molgó, Frédéric A Meunier   +9 more
doaj   +1 more source