Results 41 to 50 of about 1,646 (159)
Structure Activity Relationship of Brevenal Hydrazide Derivatives
Marine Drugs, 2014 Brevenal is a ladder frame polyether produced by the dinoflagellate Karenia brevis. This organism is also responsible for the production of the neurotoxic compounds known as brevetoxins. Ingestion or inhalation of the brevetoxins leads to adverse effects
Allan Goodman +6 more
doaj +1 more source
Acute Effects of Brevetoxin-3 Administered via Oral Gavage to Mice
Marine Drugs, 2023 Brevetoxins (BTXs) constitute a family of lipid-soluble toxic cyclic polyethers mainly produced by Karenia brevis, which is the main vector for a foodborne syndrome known as neurotoxic shellfish poisoning (NSP) in humans.
Peggy Barbe +6 more
doaj +1 more source
Brevenal inhibits pacific ciguatoxin-1B-induced neurosecretion from bovine chromaffin cells.
PLoS ONE, 2008 Ciguatoxins and brevetoxins are neurotoxic cyclic polyether compounds produced by dinoflagellates, which are responsible for ciguatera and neurotoxic shellfish poisoning (NSP) respectively. Recently, brevenal, a natural compound was found to specifically
César Mattei +9 more
doaj +1 more source
Marine Neurotoxins’ Effects on Environmental and Human Health: An OMICS Overview
Marine Drugs, 2021 Harmful algal blooms (HAB), and the consequent release of toxic metabolites, can be responsible for seafood poisoning outbreaks. Marine wildlife can accumulate these toxins throughout the food chain, which presents a threat to consumers’ health.
Sophie Guillotin, Nicolas Delcourt
doaj +1 more source
Convergent, Stereoselective Synthesis of the GHIJ Fragment of Brevetoxin A
, 2016 A stereoselective synthesis of the GHIJ fragment of brevetoxin A utilizing a convergent assembly strategy is described. Glycolate alkylation, ring-closing metathesis, and Hosomi−Sakurai reactions were central operations in the construction of the G ring ...
Michael T. Crimmins (1317639) +3 more
core +2 more sources
Characterization of Interaction Between Brevetoxin and Its Native Receptor and Identification of the Role of Brevetoxin in Karenia brevis [PDF]
, 2016 Algae are important to marine and fresh-water ecosystems. However, some species of algae are harmful or even toxic. They can consume oxygen or block sunlight that is essential for other organisms to live. Indeed, some algae blooms can produce toxins that
Chen, Wei
core +1 more source
Marine Drugs, 2015 Regular occurrence of brevetoxin-producing toxic phytoplankton in commercial shellfishery areas poses a significant risk to shellfish consumer health. Brevetoxins and their causative toxic phytoplankton are more limited in their global distribution than
Andrew D. Turner +6 more
doaj +1 more source
Fluorescent Receptor Binding Assay for Detecting Ciguatoxins in Fish. [PDF]
PLoS ONE, 2016 Ciguatera fish poisoning is an illness suffered by > 50,000 people yearly after consumption of fish containing ciguatoxins (CTXs). One of the current methodologies to detect ciguatoxins in fish is a radiolabeled receptor binding assay (RBA(R)).
D Ransom Hardison +11 more
doaj +1 more source
Toxins, 2021 In this study, Karenia brevis 165 (K. brevis 165), a Chinese strain, was used to research brevetoxin (BTX) metabolites. The sample pretreatment method for the enrichment of BTX metabolites in an algal culture medium was improved here.
Huihui Shen +6 more
doaj +1 more source
Marine Drugs, 2021 In recent decades, more than 130 potentially toxic metabolites originating from dinoflagellate species belonging to the genus Karenia or metabolized by marine organisms have been described.
Vincent Hort +4 more
doaj +1 more source