Results 31 to 40 of about 1,200 (183)

Brevetoxin and Conotoxin Interactions with Single-Domain Voltage-Gated Sodium Channels from a Diatom and Coccolithophore

Marine Drugs, 2021
The recently characterized single-domain voltage-gated ion channels from eukaryotic protists (EukCats) provide an array of novel channel proteins upon which to test the pharmacology of both clinically and environmentally relevant marine toxins.
Ping Yates, Julie A. Koester, Alison R. Taylor   +2 more
doaj   +1 more source

First Light Demonstration of Red Solar Induced Fluorescence for Harmful Algal Bloom Monitoring

Geophysical Research Letters, Volume 50, Issue 13, 16 July 2023., 2023
Abstract The risks harmful algal blooms (HAB) pose to aquatic ecosystems, public health, and coastal economies necessitate supplementation of current observation strategies. Herein, we explore the use of red solar induced fluorescence (SIF) from the TROPOspheric Monitoring Instrument (TROPOMI), a remote sensing measurement retrievable in variable cloud
Kelly Luis, Philipp Köhler, Christian Frankenberg, Michelle Gierach   +3 more
wiley   +1 more source

Potential Threats Posed by New or Emerging Marine Biotoxins in UK Waters and Examination of Detection Methodology Used in Their Control: Brevetoxins

Marine Drugs, 2015
Regular occurrence of brevetoxin-producing toxic phytoplankton in commercial shellfishery areas poses a significant risk to shellfish consumer health. Brevetoxins and their causative toxic phytoplankton are more limited in their global distribution than
Andrew D. Turner, Cowan Higgins, Keith Davidson, Andrea Veszelovszki, Daniel Payne, James Hungerford, Wendy Higman   +6 more
doaj   +1 more source

When the Red Tide Rolls In: A Red Tide Associated Angioedema Case Report

Clinical Practice and Cases in Emergency Medicine, 2021
Introduction: Histamine-mediated angioedema is a potentially life-threatening reaction following exposures that incite mast cell activation. In Florida, red tides are a frequent phenomenon caused by overgrowth of the harmful algae species Karenia brevis,
Sarah Rabinowitz, Joshua J. Solano
doaj   +1 more source

First Case of Brevetoxicosis Linked to Rough-Toothed Dolphin (Steno bredanensis) Mass-Mortality Event in Eastern Central Atlantic Ocean: A Climate Change Effect?

Frontiers in Marine Science, 2022
Harmful algal blooms (HABs) have been increasingly recorded over the last decades and much work has linked these events to multiple oceanographic and climate disturbances.
Antonio Fernández, Eva Sierra, Manuel Arbelo, Ana Gago-Martínez, Jose Manuel Leao Martins, Natalia García-Álvarez, Yara Bernaldo de Quiros, Marina Arregui, Ana Isabel Vela, Ana Isabel Vela, Josue Díaz-Delgado   +10 more
doaj   +1 more source

Emerging Marine Biotoxins in European Waters: Potential Risks and Analytical Challenges

Marine Drugs, 2022
Harmful algal blooms pose a challenge regarding food safety due to their erratic nature and forming circumstances which are yet to be disclosed. The best strategy to protect human consumers is through legislation and monitoring strategies. Global warming
Paz Otero, Marisa Silva
doaj   +1 more source

Synthesis, Modeling, and Biological Evaluation of Analogues of the Semisynthetic Brevetoxin Antagonist β‐Naphthoyl‐Brevetoxin [PDF]

ChemBioChem, 2007
AbstractBrevetoxins are neurotoxic compounds produced by the dinoflagellate Karenia brevis. Extensive blooms induce neurotoxic shellfish poisoning (NSP) and asthma‐like symptoms in humans. β‐naphthoyl‐brevetoxin, the first semisynthetic brevetoxin antagonist, has been defined as the lead compound in the investigation of the mechanisms of ...
Sophie, Michelliza, William M, Abraham, Henry M, Jacocks, Thomas, Schuster, Daniel G, Baden   +4 more
openaire   +2 more sources

Evaluation of Harmful Algal Bloom Outreach Activities

Marine Drugs, 2007
With an apparent increase of harmful algal blooms (HABs) worldwide,healthcare providers, public health personnel and coastal managers are struggling toprovide scientifically-based appropriately-targeted HAB outreach and education.
Richard Weisman, Julie Hollenbeck, Sharon Watkins, Kate Nierenberg, Lorraine Backer, Barbara Kirkpatrick, Andrew Reich, Judy A. Bean, Amy Cassedy, Wendy Blair Blair Stephan, Eva Jerez, Lora E. Fleming   +11 more
doaj   +1 more source

Brevetoxin derivatives that inhibit toxin activity [PDF]

Chemistry & Biology, 2000
The brevetoxins are marine neurotoxins that interfere with the normal functions of the voltage-gated Na(+) channel. We have identified two brevetoxin derivatives that do not exhibit pharmacological properties typical of the brevetoxins and that function as brevetoxin antagonists.PbTx-3 and benzoyl-PbTx-3 elicited Na(+) channel openings during steady ...
Purkerson-Parker, Sherry L, Fieber, Lynne A, Rein, Kathleen S, Podona, Tchao, Baden, Daniel G   +4 more
openaire   +2 more sources

Spectroscopic ellipsometry methods for brevetoxin detection

Talanta, 2022
The spectroscopic ellipsometry (SE), and attenuated internal reflection spectroscopic ellipsometry (TIRE) are promising methods in label-free biosensing applications. An ellipsometer running under surface plasmon resonance (SPR) conditions has unique advantages over other SPR-based methods in terms of sensitivity and real-time/label-free measurement ...
Mustafa Oguzhan Caglayan, Zafer Üstündağ, Samet Şahin   +2 more
openaire   +2 more sources