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Brevetoxin derivatives that inhibit toxin activity [PDF]

open access: yesChemistry and Biology, 2000
The brevetoxins are marine neurotoxins that interfere with the normal functions of the voltage-gated Na(+) channel. We have identified two brevetoxin derivatives that do not exhibit pharmacological properties typical of the brevetoxins and that function as brevetoxin antagonists.PbTx-3 and benzoyl-PbTx-3 elicited Na(+) channel openings during steady ...
Kathleen Rein   +2 more
exaly   +3 more sources
Some of the next articles are maybe not open access.

Total Synthesis of Brevetoxin A: Part 4: Final Stages and Completion

Chemistry - A European Journal, 1999
Kyriacos Nicolaou
exaly  

Brevetoxin — an elusive toxin in New Zealand waters

African Journal of Marine Science, 2006
L Rhodes
exaly  

Total Synthesis of Brevetoxin A: Part 3: Construction of GHIJ and BCDE Ring Systems

Chemistry - A European Journal, 1999
Kyriacos Nicolaou
exaly  

Synthetic studies on brevetoxin-B. Part 1: Stereoselective synthesis of the ABC-ring system

Tetrahedron Letters, 2000
Nobuyuki Hori   +2 more
exaly  

Brevetoxin-2 induces an inflammatory response in an alveolar macrophage cell line

International Journal of Hygiene and Environmental Health, 2010
John Baatz, Kelli Sas
exaly  

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