Results 21 to 30 of about 1,538 (200)

The Cardioprotective Potential of Marine Venom and Toxins [PDF]

open access: yesToxins
Cardiovascular disease (CVD) continues to be the primary cause of morbidity and mortality worldwide, underscoring the urgent need for novel therapeutic alternatives.
Virginia Heaven Mariboto Siagian   +1 more
doaj   +2 more sources

HABs Karenia brevis and Pseudo-nitzschia pre- and post-Hurricane Michael [PDF]

open access: yesJournal of Water and Health, 2023
Increased occurrences of harmful algal blooms (HAB) in the Gulf of Mexico, and even worldwide, yield concern for increases in brevetoxin exposure leading to respiratory illness or even death, highlighting the need for extensive scientific research and ...
Josh Alarcon   +8 more
doaj   +2 more sources

Characterization of Interaction Between Brevetoxin and Its Native Receptor and Identification of the Role of Brevetoxin in Karenia brevis

open access: yes, 2017
Algae are important to marine and fresh-water ecosystems. However, some species of algae are harmful or even toxic. They can consume oxygen or block sunlight that is essential for other organisms to live. Indeed, some algae blooms can produce toxins that
Chen, Wei
openaire   +4 more sources

Predicting <i>Karenia brevis</i> Induced Respiratory Irritation at Individual Southwest Florida Beaches Using Cell Abundances Plus Wind Direction and Speed. [PDF]

open access: yesGeohealth
Abstract Nearly annually, blooms of the dinoflagellate Karenia brevis form along the southwest Florida coast leading to a variety of negative impacts, including respiratory irritation (RI) in humans. To limit these impacts, NOAA's National Centers for Coastal Ocean Science (NCCOS) developed a RI model to provide beach‐goers with a category‐based ...
Collins KM   +6 more
europepmc   +2 more sources

Effects of in vitro Brevetoxin Exposure on Apoptosis and Cellular Metabolism in a Leukemic T Cell Line (Jurkat)

open access: yesMarine Drugs, 2008
Harmful algal blooms (HABs) of the toxic dinoflagellate, Karenia brevis, produce red tide toxins, or brevetoxins. Significant health effects associated with red tide toxin exposure have been reported in sea life and in humans, with brevetoxins documented
John W. Sleasman   +4 more
doaj   +2 more sources

Synthesis of the A-F Fragment of the Pacific Ciguatoxin CTX3C by Iterative Ring-Closing Metathesis and Tsuji-Trost Allylation. [PDF]

open access: yesChemistry, 2023
The fully functionalized A−F ring system of the Pacific ciguatoxin CTX3C suitable for coupling to the I−M fragment of the natural product, has been synthesized from a simple glucal derivative. A six‐step sequence that features ring‐closing metathesis and stereoselective palladium‐mediated allylation has been deployed in an iterative manner to construct
Triantafyllakis M   +4 more
europepmc   +2 more sources

Guidance Level for Brevetoxins in French Shellfish [PDF]

open access: yesMarine Drugs, 2021
Brevetoxins (BTXs) are marine biotoxins responsible for neurotoxic shellfish poisoning (NSP) after ingestion of contaminated shellfish. NSP is characterized by neurological, gastrointestinal and/or cardiovascular symptoms. The main known producer of BTXs is the dinoflagellate Karenia brevis, but other microalgae are also suspected to synthesize BTX ...
Arnich, Nathalie   +10 more
openaire   +6 more sources

Detection of Brevetoxin in Human Plasma by ELISA. [PDF]

open access: yesJ Anal Toxicol, 2022
Abstract Florida red tides have become more common and persistent in and around the Gulf of Mexico. When in bloom, red tides can produce brevetoxins in high concentrations, leading to human exposures primarily through contaminated food and ocean spray.
Cunningham BR   +4 more
europepmc   +4 more sources

Development of a New Monoclonal Antibody against Brevetoxins in Oyster Samples Based on the Indirect Competitive Enzyme-Linked Immunosorbent Assay

open access: yesFoods, 2021
The consumption of shellfish contaminated with brevetoxins, a family of ladder-frame polyether toxins formed during blooms of the marine dinoflagellate Karenia brevis, can cause neurotoxic poisoning, leading to gastroenteritis and neurotoxic effects.
Xiya Zhang   +8 more
doaj   +1 more source

Total Synthesis of Brevetoxin-B [PDF]

open access: yesJournal of the American Chemical Society, 2003
Brevetoxin-B (BTX-B), produced by the red tide organism, Gymnodium breve Davis, is the first member of marine polycyclic ethers to be structurally elucidated and one of the most potent neurotoxins. The structural feature is a trans-fused polycyclic ether ring system with 23 stereocenters.
Goh, Matsuo   +4 more
openaire   +2 more sources

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