Results 1 to 10 of about 3,559 (85)

Halide Bond Assisted Double Desymmetrization of Meso-Dicarboxylic Acids with Symmetrical Olefins via Asymmetric Halogenation. [PDF]

Angew Chem Int Ed Engl
This work demonstrates a double desymmetrization of meso‐dicarboxylic acids with symmetrical olefins, constructing complex chiral lactones with six stereocenters in one step. Unexpectedly, the halide bond was found to be crucial in achieving high stereoselectivity.
Zhang Q, Wang H, Tse YS, Yeung YY.
europepmc   +3 more sources

(Poly)Borylated Species as Modern Reactive Groups toward Unusual Synthetic Applications

Angewandte Chemie, Volume 138, Issue 10, 2 March 2026.
In this review, we spotlight recent breakthroughs in α‐polyboron‐substituted carbon‐centered intermediates (carbanion, carbocation, radical, and carbene) and polyborylated alkenes. By bridging fundamental reactivity with the application potential of these extraordinary species, we hope this review will serve as a roadmap for harnessing these unique ...
Nadim Eghbarieh, Nicole Hanania, Pinaki Nad, Tipu Alam, Tamir Kish, Ahmad Masarwa   +5 more
wiley   +2 more sources

Structural‐to‐Functional Complexity Transformations Enabled by Bridged Polyheterocycles: Access to Cis‐1,3‐Diamines and Amino‐Alcohols

ChemistryEurope, Volume 4, Issue 6, June 2026.
Polycyclic intermediates enable stereocontrolled synthesis of densely functionalized cis‐1,3‐diamine and amino alcohol carbocycles and heterocycles via structural‐to‐functional complexity transformations from low‐complexity starting material. Cis‐1,3‐functionalized carbocycles and saturated heterocycles are ubiquitous motifs in natural products ...
Jiayi Zhu, Erica Benedetti, Laurent Micouin   +2 more
wiley   +1 more source

Pure Molecular Inorganic Rings: Mixed Group 14/15 Metallacycles

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
The synthesis and characterization of novel mixed group 14/15 metallacycles incorporating a transition‐metal is described. All of the presented compounds were obtained by reduction of an organometallic Mo2E2 tetrahedrane using Si(I) and Ge(I) compounds, respectively.
Stefanie Maier, Xiaofei Sun, Lisa Zimmermann, Ralf Köppe, Manfred Scheer, Peter W. Roesky   +5 more
wiley   +2 more sources

Divergent Synthesis of Polycyclic Derivatives via Gold Catalysis

European Journal of Organic Chemistry, Volume 29, Issue 20, 27 May 2026.
Gold(I)‐catalyzed cycloisomerization enables the formation of complex 3D structures from simple enyne precursors. This study presents a divergent strategy to synthesize functionalized bicyclic and tricyclic scaffolds from a common alkynyl ketone.
Emilie Gentilini, Vincent Davenel, Pierre Ligonès, Jean‐Marie Fourquez, Véronique Michelet   +4 more
wiley   +1 more source

GC × GC‐TOF MS and Sensory Profiling of Aroma Compounds in Magnolia Species: Effects of Processing Methods on Volatile Retention in M. wufengensis

Flavour and Fragrance Journal, Volume 41, Issue 3, Page 487-503, May 2026.
The first comparative analysis of Magnolia scents reveals that M. wufengensis is characterised by a high aldehyde content, exhibiting a fresh, sweet, and fruity fragrance profile. Furthermore, freeze‐drying preserves 6.7 times more 2‐nonenal compared to shade‐drying, highlighting its superior efficacy in retaining key volatile compounds.
Xiaole Wang, Zhonghua Du, Lei Xu, Junjie Hu, Tao Xiong, Chiqing Chen, Lichun Ye, Zhaohua Shi   +7 more
wiley   +1 more source

Uniqueness of Supramolecular Systems

Macromolecular Materials and Engineering, Volume 311, Issue 5, May 2026.
Thanks to the variety of classes of supramolecular systems, they have been widely used in various applications. For example, in sensing devices, catalysis, and biomedicine. An example of a conventional photovoltaic material converted into electrical energy. Selective UV or NIR absorbers are required to produce materials with low or no coloration.
José A. Sánchez‐Fernández
wiley   +1 more source

Modular Access to Bridgehead Heterocycle‐Substituted Bicyclo[1.1.0]butanes via Late‐Stage Functionalization of Alkynylbicyclo[1.1.0]butanes

Chemistry–Methods, Volume 6, Issue 4, April 2026.
A modular late‐stage manifold exploits the embedded alkyne of alkynylbicyclo[1.1.0]butanes (ABCBs) to deliver triazole‐, isoxazole‐, free‐NH‐pyrrole, free‐NH‐pyrazole, or silacyclohexene‐decorated BCBs in a single operation. Strain‐release transformations of bicyclo[1.1.0]butanes are powerful methods for constructing four‐membered rings and bicyclo[n.1.
Yu‐Jie Li, Quanxin Peng, Wen‐Biao Wu, Jian‐Jun Feng   +3 more
wiley   +1 more source

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

Cancer Nexus, Volume 2, Issue 2, April 2026.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang   +5 more
wiley   +1 more source

From Design to Bioactivity: 2‐Benzoylpyridine 4‐(bicyclo[2.2.1]hept‐2‐yl)thiosemicarbazone and Its 3d Metal Coordination Compounds

ChemistryOpen, Volume 15, Issue 4, April 2026.
The new 2‐benzoylpyridine 4‐(bicyclo[2.2.1]hept‐2‐yl)thiosemicarbazone (HL) and its copper(II), nickel(II), cobalt(III), and iron(III) coordination compounds [Cu(L)Cl] (1), [Cu(L)NO3] (2), {[Cu(L)(Cl2CHCOO)]}n (3), [Ni(HL)2](NO3)2 (4), [Fe(L)2]NO3 (5), [Co(L)2]NO3 (6) were obtained.
Ianina Graur, Vasilii Graur, Elena Melnic, Carolina Lozan‐Tirsu, Greta Balan, Victor Tsapkov, Aurelian Gulea   +6 more
wiley   +1 more source