Results 1 to 10 of about 2,106,514 (153)

Bridged Bicyclic Building Block Upgrading: Photochemical Synthesis of bicyclo[3.1.1]heptan-1-Amines [PDF]

, 2020
Compounds containing bridged bicyclic carbon skeletons are desirable building blocks for medicinal chemistry. However, as a result of their inefficient, linear syntheses, commercially available compounds of this sort are plagued by high costs and/or a ...
Alexander S. Harmata, Madison J. Sowden, C. Stephenson   +2 more
semanticscholar   +2 more sources

Photoinduced [4 + 2]-cycloaddition reactions of vinyldiazo compounds for the construction of heterocyclic and bicyclic rings

Chemical Science
Highly selective formal [4 + 2]-cycloaddition of vinyldiazoacetates with azoalkenes from α-halohydrazones, as well as with cyclopentadiene and furan, occurs with light irradiation at room temperature, producing highly functionalized heterocyclic and ...
Ming Bao, A. R. Romero Bohorquez, Hadi D Arman, Michael P. Doyle   +3 more
semanticscholar   +1 more source

Annulation of Hydroxyarenes and Derivatives with Bicyclo[1.1.0]butanes by Synergistic Combination of Metal Lewis Acid and Organic Acid

JACS Au
The development of new approaches to synthesize complex structures from readily available compounds is a topic of significant interest in synthetic chemistry.
Qihang Guo, Dong-Shun Ni, Lisa X. Deng
semanticscholar   +1 more source

Catalytic asymmetric tandem Heck/Sonogashira reaction enabling access to versatile chiral bridged ring scaffolds

Nature Communications
Bridged-ring scaffolds are prevalent in numerous natural products and pharmaceuticals. However, achieving enantioselective construction of these architectures presents a significant challenge, due to the considerable structural strain of the products and
Jing Zhong, Mengxian Li, Changhui Wu, Hui Li, Hongyue Dong, Chunchen Che, Ai-Jun Lin, He-Quan Yao   +7 more
semanticscholar   +1 more source

Exploring the Therapeutic Potential of 1,3-Benzimidazole: An Auspicious Heterocyclic Framework

Oriental Journal of Chemistry
The scientific study of benzimidazole derivatives has advanced steadily due to its fascinating chemical structure with wide range of biological activities.
Shivkant Patel, A. Sen, D. Sen, Ashish Shah   +3 more
semanticscholar   +1 more source

Synthesis of 1,4-phenylene bridged bis-heterocyclic compounds

, 2011
The synthesis of 1,4-phenylene bis-heterocyclic compounds is comprehensively reviewed.
R. M. Shaker
semanticscholar   +1 more source

“Zip”Ring Expansion

, 1993
K. Sakai, Zhuofeng Xie
semanticscholar   +1 more source

Catalytic [6 + 3] cycloaddition for the synthesis of medium-sized ring systems: a critical review. [PDF]

RSC Adv
Archna, Kumar G, Chawla PA, Kumar R, Bhargava G.   +4 more
europepmc   +1 more source

Venetoclax-Induced Symmetrical Drug-Related Intertriginous and Flexural Exanthema (SDRIFE): Implications for Diagnosis and Treatment Continuation. [PDF]

J Dermatol
Tanaka N, Iso A, Higashime A.
europepmc   +1 more source

Lewis Acid-Catalyzed Strain-Enabled (3+3) Annulation of Bicyclo[1.1.0]Butanes With Indolylalcohols: Synthesis of Indole-Fused Aza-Bicyclo[3.1.1]Heptanes. [PDF]

Adv Sci (Weinh)
Dey M, Mahapatra TSD, Sharma P, Mane MV, Hazra CK.   +4 more
europepmc   +1 more source