Results 11 to 20 of about 1,695,530 (119)
Studies of novel nitro-substituted nitrogen heterocyclic compounds [PDF]
, 2001 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The novel candidate high energy insensitive explosive; 2,5-diamino-3,6-dinitropyrazine (ANPZ-i) has been prepared in acceptable overall yield.
Philbin, Simon Patrick
core +7 more sources
Bridged Bicyclic Compounds [PDF]
, 1973 This thesis is concerned with certain aspects of the application of Bredt's Rule in bridged bicyclic compounds. The reported monodecarboxylation of bicyclo[2,2,2]-octane-2,5-dione-1,4-dicarboxylic acid (1) to give bicyclo-[2,2,2]octane-2,5-dione-l ...
Kean, Norman Buchanan
core +6 more sources
Bridged Bicyclic Building Block Upgrading: Photochemical Synthesis of bicyclo[3.1.1]heptan-1-Amines [PDF]
, 2020 Compounds containing bridged bicyclic carbon skeletons are desirable building blocks for medicinal chemistry. However, as a result of their inefficient, linear syntheses, commercially available compounds of this sort are plagued by high costs and/or a ...
Alexander, Harmata +2 more
core +1 more source
Bicyclo[m.n.k]alkane Building Blocks as Promising Benzene and Cycloalkane Isosteres: Multigram Synthesis, Physicochemical and Structural Characterization [PDF]
, 2023 Electrophilic double bond functionalization – intramolecular enolate alkylation sequence was used to obtain a series of bridged and fused bicyclo[m.n.k]alkane derivatives (i.e., bicyclo[4.1.1]octanes, bicyclo[2.2.1]heptanes, bicyclo[3.2.1]octanes ...
Ihor, Fesun +9 more
core +1 more source
Angewandte Chemie, EarlyView.Catalytic strain‐release ring opening and functionalizations of 1‐azabicyclo[1.1.0]butanes (ABBs) represent a promising strategy for accessing diverse azetidine products. These transformations proceed via polar pathways, radical pathways, and hybrid mechanisms that combine both.
James Shao‐Jiun Yang +1 more
wiley +2 more sources
Angewandte Chemie, EarlyView.A metal‐free photocatalytic platform converts nitrones into 4‐isoxazolines and oxa–aza–bicycloheptanes through divergent [3+2π/σ] cycloadditions. Assembly‐controlled kinetic electron transfer gating dictates substrate activation, enabling selective reactivity beyond thermodynamic expectations.
Nayan Saha +6 more
wiley +2 more sources
Remapping the Synthetic Landscape of α‐Tertiary Alkylamines via Dual‐Functional Catechol
Angewandte Chemie, Volume 138, Issue 37, 7 September 2026.A three‐component assembly strategy has been developed for the modular synthesis of hindered α‐tertiary aliphatic amines from readily available precursors through unlocking the dual role of catechol. The practicality of this methodology has been demonstrated in over 90 examples, including compounds that are otherwise difficult to access, along with ...
Chen‐Yan Cai, Yuzuru Kanda, Tian Qin
wiley +2 more sources
, 2016 A 1,6 conjugate addition/Nazarov electrocyclization/internal redox cyclization sequence was developed. Various 5-hydroxycyclopentenones were made through the 1,6-conjugate addition initiated Nazarov reaction with excellent diastereoselectivities.
Alison J. Frontier (1307097) +1 more
core +2 more sources
An NHC‐Coordinated Silicon/Sulfur Analogue of an Acyl Carbene
Angewandte Chemie, Volume 138, Issue 35, 24 August 2026.An NHC complex of an Si/S analogue of an acyl carbene is synthesized by the reaction of a disilyne with a cyclic thiourea. The observed Si2S three‐membered ring with unsymmetrical Si─S distances and a Si─Si single bond is consistent with intramolecular coordination of the silathioacyl sulfur to the silylene center.
Takuto Toyooka +2 more
wiley +2 more sources
European Journal of Organic Chemistry, EarlyView.A simple, modular, and unified strategy for the synthesis of reverse‐prenylated hexahydropyrrolo indole alkaloids has been developed. An unusual retrosynthetic disconnection allows for the late introduction of a side chain, which distinguishes many members of this class of natural products.
Daniel Schmelzer +2 more
wiley +1 more source