Results 71 to 80 of about 1,691,933 (287)

Liquid morphologies and capillary forces between three spherical beads

open access: yes, 2015
Equilibrium shapes of coalesced pendular bridges in a static assembly of spherical beads are computed by numerical minimization of the interfacial energy.
Brinkmann, Martin   +4 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Transverse mode control and switching in gas laser arrays [PDF]

open access: yes, 1994
Theoretical and experimental investigations of multiple transverse mode laser oscillation involving spatially varying gain and loss are carried out. The effect of gain and loss distribution on mode competition is analyzed.
Bridges, William B., Zhang, Yongfang
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Numerical Simulation Strategy of Reinforced Concrete Tunnel Bearing Members in Fire

open access: yesThe Baltic Journal of Road and Bridge Engineering, 2006
Reinforced concrete structures subjected to fire will generally experience a complex behaviour. This paper presents a strategy of numerical simulation of reinforced concrete members exposed to high temperatures and subjected to external loading.
Viktor Gribniak   +2 more
doaj  

CFRP Materials for Restoration of the Bearing Capacity of RC Beams With Damaged Rebar

open access: yesJournal of Engineering
Corrosion of the rebar in reinforced concrete (RC) structures is a critical concern, compromising their reliability and long-term operation. Carbon fibre–reinforced polymer (CFRP) tapes are widely used for strengthening RC structures due to their ...
Nadiia Kopiika   +5 more
doaj   +1 more source

Administrative responsibility in achieving the administrative control of the Public Road service - comparison study [PDF]

open access: yesالرافدین للحقوق
This study deals with the function of administrative control, in which public roads are considered the most important field. However, the administration is required to provide satisfying public traffic for individuals, and at the same time, it is ...
Ahmed Abdullah, Abubker Alnuimee
doaj   +1 more source

Hong Kong\u27s dual identities and sporting mega-event policy

open access: yes, 2013
Since Hong Kong\u27s reversion to China in 1997, the Special Administrative Region\u27s government and its people have grappled with the problem of trying to pursue dual objectives at the same time. Firstly, to adjust to being a \u27new\u27 part of China
BRIDGES, Brian
core  

Wright-Fisher diffusion bridges [PDF]

open access: yes, 2017
{\bf Abstract} The trajectory of the frequency of an allele which begins at $x$ at time $0$ and is known to have frequency $z$ at time $T$ can be modelled by the bridge process of the Wright-Fisher diffusion.
Griffiths, Robert   +2 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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