Results 41 to 50 of about 1,119,897 (288)

Bridging Organizational Silos [PDF]

, 2010
{Excerpt} A silo is a tall, self-contained cylindrical structure that isused to store commodities such as grain after a harvest. It is also a figure of speech for organizational entities—and their management teams—that lack the desire or motivation to ...
Serrat, Olivier
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Experimental Study on Reasonable Steam Curing Scheme of Prefabrication Box Girder

Advances in Civil Engineering
The assembly-line production mode was adopted to meet the production demands of prefabricated box girders for the Haiyan line. The steam curing method was introduced to accelerate concrete strength development, allowing the prestressing tension ...
Changpo Li, Chaoyu Zhu
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Bridging the Disconnect [PDF]

, 2014
New York City is facing a youth unemployment crisis, but the city's youth workforce development programs reach only a fraction of those in need of help and are too often misaligned to the developmental needs of young New ...
Christian Gonzales-Rivera, David Jason Fischer, Jonathan Bowles   +2 more
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Structure of a model salt bridge in solution investigated with 2D-IR spectroscopy [PDF]

, 2013
Salt bridges are known to be important for the stability of protein conformation, but up to now it has been difficult to study their geometry in solution.
Amirjalayer, Saeed, Domingos, Sérgio R., Huerta-Viga, Adriana, Woutersen, Sander   +3 more
core   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Exploring structural and electronic effects in three isomers of tris{bis(trifluoromethyl)phenyl}borane: Towards the combined electrochemical-frustrated Lewis pair activation of H2 [PDF]

, 2015
Three structural isomers of tris{bis(trifluoromethyl)phenyl}borane have been studied as the acidic com- ponent of frustrated Lewis pairs. While the 3,5-substituted isomer is already known to heterolytically cleave H2 to generate a bridging-hydride; ortho-
Andrew E. Ashley, Becke, Binding, Bourhis, Chapman, Chase, Chernichenko, Clark, Coles, Cornet, Dolomanov, Elliot J. Lawrence, Farrell, Fulmer, Gregory G. Wildgoose, Hariharan, Heiden, Herrington, Katie Resner, Kolychev, Konze, Lancaster, Lawrence, Lawrence, Lawrence, Lawrence, Lee, LeSuer, Lu, Mahdi, McDaniel, Melen, Ménard, Ménard, Palatinus, Palatinus, Palatinus, Robin J. Blagg, Rokob, Scott, Scott, Sheldrick, Sheldrick, Sivaev, Stephan, Stephan, Stephan, Stephan, Stephan, Stephan, Thomas J. Herrington, Vasily S. Oganesyan, Wang, Welch, Wu, Xu   +55 more
core   +1 more source