Results 71 to 80 of about 529,068 (299)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Bridging bonds: Latvian migrants’ interpersonal ties on social networking sites
, 2018 Conflicting accounts exist regarding the influence of online-based communication platforms on the development of cross-border migrants’ networks. It has been reported that such platforms can either promote migrants’ participation in the host society or ...
Ianis Bucholtz
core +1 more source
Network Simulation Bridge: Bridging Applications to Network Simulators
Proceedings of the 19th ACM International Symposium on QoS and Security for Wireless and Mobile Networks, 2023 Harikrishna S. Kuttivelil +4 more
openaire +3 more sources
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Problems and Prospects in Automation and Networking in Libraries in India [PDF]
, 2010 This article presents Scenario of Automation and the networking of academic libraries are still in their formative stages. The reasons for, prerequisites of, and benefits of networking are given.
Pradip, Joshi, Nikose, S.M.
core +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Evaluating the user perceived usefulness of enterprise social networking [PDF]
, 2014 This paper aims to identify user perceived usefulness of enterprise social networking within the public and private sector of Wellington NZ. It aims at determining the specific factors that appeal to enterprise social networking users.
Naveen Vaseegaran +2 more
core +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Is thin-client becoming the new paradigm in networking technologies? A research paper for the course Networking Technologies at the Master in Library Science program, Department of Library and Information Studies, State University of New York at Buffalo (USA) [PDF]
, 2000 This is a research paper for the course of Networking Technologies at the Master of Library Science, Dept. of Library and Information Studies, State University of New York at Buffalo; Professor of the course Neil Yerkey, December 11, 2000.
Muela-Meza, Zapopan Martín
core +1 more source