Results 11 to 20 of about 8,176 (221)
Patient Preference and Adherence, 2017 Michael S Anderson,1 Anish Nadkarni,1 Leah A Cardwell,1 Hossein Alinia,1 Steven R Feldman1–3 1Department of Dermatology, Center for Dermatology Research, 2Department of Pathology, 3Department of Public Health Sciences, Wake Forest School of ...
Anderson MS +4 more
doaj +3 more sources
Is brimonidine ophthalmic a safe therapy for infants?
Journal of Clinical Pharmacy and Therapeutics, 2006 Brimonidine is a topical alpha-2 agonist commonly used in the treatment of glaucoma. Brimonidine toxicity resembles that of clonidine overdose and is probably due to both imidazoline and alpha-2 adrenergic receptor effects. We report a case of a 6-week-old infant with congenital glaucoma who developed bradycardia and hypotension following the ...
G. Patrick Daubert
openalex +4 more sources
Prolonged central nervous system and respiratory depression in preterm neonates after exposure to brimonidine tartrate and timolol maleate ophthalmic drops [PDF]
GMS Ophthalmology Cases, 2020 Objective: We report three cases of preterm neonates who presented with central nervous system (CNS) and respiratory depression after inadvertent exposure to brimonidine tartrate 0.2% and timolol maleate 0.5% fixed-combination ophthalmic drops.Case ...
Azarcon, Corrina P., Santiago, Darby E.
doaj +2 more sources
Brimonidine prevents axonal and somatic degeneration of retinal ganglion cell neurons [PDF]
Molecular Neurodegeneration, 2011 Background Brimonidine is a common drug for lowering ocular pressure and may directly protect retinal ganglion cells in glaucoma. The disease involves early loss of retinal ganglion cell transport to brain targets followed by axonal and somatic ...
Crish Samuel D +4 more
doaj +5 more sources
The potential of brimonidine for myopia treatment: Targeting MMP-2 to regulate choroidal thickness and control eye growth [PDF]
HeliyonDrug treatment studies are a focal point for identifying novel approaches to reduce myopia progression through basic science research. Here, we investigated the effects of various brimonidine administration routes and concentrations on form-deprivation ...
Aiqun Xiang +8 more
doaj +2 more sources
Effect of a fixed combination of ripasudil and brimonidine on aqueous humor dynamics in mice [PDF]
Scientific ReportsRipasudil–brimonidine fixed-dose combination (K-232) simultaneously targets three different intraocular pressure (IOP) lowering mechanisms, increasing trabecular meshwork outflow and uveoscleral outflow, and reducing aqueous humor production Vascularly ...
Reiko Yamagishi-Kimura +2 more
doaj +2 more sources
The role of brimonidine tartrate gel in the treatment of rosacea
Clinical, Cosmetic and Investigational Dermatology, 2015 Rosacea is a chronic cutaneous condition with a prevalence rate ranging from 9.6% to 22% in recent studies. Facial erythema (transient and permanent) is considered a common denominator that is frequently observed in all subtypes of rosacea and is estimated to affect more than 40 million people worldwide.
Jackson JM +4 more
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Brimonidine Eye Drops within the Reach of Children: A Possible Foe [PDF]
ChildrenBrimonidine, a selective alpha-2 adrenergic agonist used for the treatment of open-angle glaucoma, has been shown to cause neurological side effects such as unresponsiveness, lethargy, hypoventilation, and stupor, mimicking opioid toxicity. We report one
Daniela Trotta +5 more
doaj +2 more sources
Switching to Brimonidine/Ripasudil Fixed Combination from Brimonidine + Ripasudil
Clinical OphthalmologyKenji Inoue,1 Minako Shiokawa,1 Shiho Kunimatsu-Sanuki,2 Goji Tomita,1,3 Kyoko Ishida3 1Inouye Eye Hospital, Tokyo, Japan; 2Nishikasai Inouye Eye Hospital, Tokyo, Japan; 3Department of Ophthalmology, Toho University Ohashi Medical Center, Tokyo ...
Inoue K +4 more
doaj +3 more sources
Офтальмохирургия, 2021 Purpose. To present data on the mechanism of action, efficacy, and side effects of various brimonidine dosage forms in the treatment of glaucoma and ocular hypertension.Material and methods. To perform the review, literature sources were searched through
A. V. Sidorova +3 more
doaj +1 more source